Role of Mapping and Ablation in Genetic Diseases: Long QT Syndrome and Catecholaminergic Polymorphic Ventricular Tachycardia

Steven J. Fowler, Larry A. Chinitz, Silvia G. Priori

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Management of patients with channelopathies represents a challenging field for the electrophysiologist because, given the absence of obvious structural abnormalities of the cardiac tissue, it is difficult to define paradigms for the use of mapping and ablation. Anecdotal reports and studies conducted in limited numbers of patients support the view that ablative procedures should be part of the clinical armamentarium used to treat ion channel disorders, yet conclusive data are far from being available. We believe that the nuanced nature of heritable arrhythmogenic disease presents distinct challenges to mapping and radiofrequency ablation; therefore, in the present chapter we review currently available studies as well as selected cases from our experience focusing on patients with long QT syndrome and catecholaminergic polymorphic ventricular tachycardia. This edition first published 2013

Original languageEnglish
Title of host publicationCardiac Mapping: Fourth Edition
PublisherWiley-Blackwell
Pages644-655
Number of pages12
ISBN (Print)9780470670460
DOIs
Publication statusPublished - Dec 18 2012

Keywords

  • Ablation
  • Catecholaminergic
  • Disease
  • Genetic
  • Inherited
  • Long QT
  • Mapping
  • Ventricular arrhythmias

ASJC Scopus subject areas

  • Medicine(all)

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