Translated title of the contribution: Role of MRI in hypoxic-hemorrhagic syndrome of the neonate

Research output: Contribution to journalArticlepeer-review


Although the role of Magnetic Resonance Imaging in the diagnostic evaluation of hypoxic-ischemic encephalopathy and germinal matrix hemorrhage is still under evaluation some advantages of this technique can be clearly defined by now. a) Germinal matrix hemorrhage. MRI can be useful in the evaluation of intraparenchymal extension of peri-intraventricular lesions. Its high sensitivity to paramagnetic hemosiderin could help to identify hemorrhages up to several months from birth. For this reason MRI can be also useful in order to identify a previous fetal hemorrhage as a cause of hydrocephalus in newborns. b) Periventricular leukomalacia. MRI is the diagnostic procedure of choice in the evaluation of the extension of the lesions. Thus its prognostic value is at present essential in the clinical assessment of this patients. c) Hypoxic-ischemic encephalopathy of fullterm newborns. Brain lesions in fullterm asphyxiated newborn are difficult to identify with traditional radiological techniques such as ultrasound and computerized tomography. MRI has recently contributed to a better understanding of the different nature of hypoxic damage within the neonatal brain. Due to its capability to identify myelinated and unmyelinated fibers it was able to recognize hypoxic lesions that involve selectively myelinated fibers and separate them from parasagittal lesions mainly due to hypotensive hypoxia.

Translated title of the contributionRole of MRI in hypoxic-hemorrhagic syndrome of the neonate
Original languageItalian
Pages (from-to)163-170
Number of pages8
JournalRivista di Neuroradiologia
Issue number2
Publication statusPublished - 1994

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


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