Abstract
Knowledge of what determines the developmental competence of oocytes during folliculogenesis is poor. This review, through the analysis of the expression profile of developmentally competent or incompetent mouse oocytes, summarizes the results of recent studies showing that the Oct-4 transcription factor regulating the expression of Stella and Foxj2 at the Nanog locus could play a pivotal role in the establishment of the oocyte's developmental competence.
| Original language | English |
|---|---|
| Pages (from-to) | 57-62 |
| Number of pages | 6 |
| Journal | Reproductive BioMedicine Online |
| Volume | 19 |
| Issue number | SUPPL. 3 |
| DOIs | |
| Publication status | Published - Dec 2009 |
Keywords
- Developmental competence
- Mouse
- Oct-4
- Oocyte
ASJC Scopus subject areas
- Reproductive Medicine
- Developmental Biology
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Zuccotti, M., Merico, V., Redi, C. A., Bellazzi, R., Adjaye, J., & Garagna, S. (2009). Role of Oct-4 during acquisition of developmental competence in mouse oocyte. Reproductive BioMedicine Online, 19(SUPPL. 3), 57-62. https://doi.org/10.1016/S1472-6483(10)60284-2