Role of postoperative radiotherapy after pelvic lymphadenectomy and radical retropubic prostatectomy: A single institute experience of 415 patients

Cesare Cozzarini, Angelo Bolognesi, Giovanni Luca Ceresoli, Claudio Fiorino, Alberto Rossa, Roberto Bertini, Renzo Colombo, Luigi Da Pozzo, Francesco Montorsi, Marco Roscigno, Riccardo Calandrino, Patrizio Rigatti, Eugenio Villa

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose To evaluate the clinical benefit deriving from early (within 6 months) radiotherapy (ERT) after pelvic lymphadenectomy and radical retropubic prostatectomy for localized/locally advanced adenocarcinoma of the prostate in a single-institution series. Methods and materials We retrospectively analyzed 415 patients who underwent pelvic lymphadenectomy and radical retropubic prostatectomy between 1986 and 1998 for pT2b-pT4, pN0-pN1 prostate carcinoma. Of the 415 patients, 237 underwent ERT for adverse pathologic findings and 178 patients did not receive RT or underwent salvage RT ≤6 months (salvage or no RT [SNRT]). Results After a median follow-up of 62 months, the 8-year actuarial freedom from biochemical, local and systemic failure, and cause-specific survival rate was 69% vs. 31% (p

Original languageEnglish
Pages (from-to)674-683
Number of pages10
JournalInternational Journal of Radiation Oncology Biology Physics
Volume59
Issue number3
DOIs
Publication statusPublished - Jul 1 2004

Keywords

  • Adjuvant radiotherapy
  • Prostatectomy
  • Prostatic neoplasms

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Radiation

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