Role of pre-emptive analgesia in reduction mammaplasty

P. Di Marco, F. R. Grippaudo, G. Della Rocca, R. De Vita

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Pre-emptive analgesia is an antinociceptive treatment that prevents altered central excitability from high intensity noxious stimuli. The aim of this study was to evaluate the efficacy of pre-emptive analgesia in patients due to have elective breast reduction that usually requires drugs for postoperative pain control. Sixty women, ASA grades I-II, were randomly divided into two groups: 30 patients were given ropivacaine infiltration 1.5 mg/ml plus adrenaline 1/200 000 in normal saline 100 ml before the skin incision, and 30 had normal saline 100 ml plus adrenaline 1/200 000 infiltrated. Postoperative pain was evaluated by an observer who was unaware of the treatment given, and scored on a visual analogue score (VAS) during the first 72 hours postoperatively. Analgesic requirements were recorded. There was a statistically significant difference between groups in the amount of additional pain control required during the early postoperative period, which suggests that pre-emptive analgesia reduces pain after reduction mammaplasty.

Original languageEnglish
Pages (from-to)297-300
Number of pages4
JournalScandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery
Volume35
Issue number3
DOIs
Publication statusPublished - 2001

Fingerprint

Mammaplasty
Analgesia
Postoperative Pain
Epinephrine
Pain
Postoperative Period
Analgesics
Breast
Skin
Therapeutics
Pharmaceutical Preparations

Keywords

  • Postoperative pain
  • Pre-emptive analgesia
  • Reduction mammaplasty
  • Ropivacaine
  • VAS

ASJC Scopus subject areas

  • Surgery

Cite this

Role of pre-emptive analgesia in reduction mammaplasty. / Di Marco, P.; Grippaudo, F. R.; Della Rocca, G.; De Vita, R.

In: Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery, Vol. 35, No. 3, 2001, p. 297-300.

Research output: Contribution to journalArticle

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