Role of prenatal diagnosis in the treatment of congenital obstructive megaureter in a solitary kidney

P. Caione, M. Patricolo, A. Lais, M. L. Capitanucci, N. Capozza, F. Ferro

Research output: Contribution to journalArticlepeer-review


Congenital megaureter in a solitary kidney (CMSK) is a life-threatening disease. From January 1988 to December 1993, we treated 9 patients for CMSK (2 cases with unilateral renal dysplasia and 7 with unilateral renal agenesis). In 7 cases, the malformation was detected by prenatal ultrasonography and urological counseling. The ages at first postnatal observation ranged from 24 h to 5 years (mean = 8 months). The postnatal urological workup included: serum renal function screening, urinary system ultrasonography, a micturition cystogram, intravenous pyelography and a nuclear renal scan. The therapy of choice was decided on the basis of renal function. One emergency divertive procedure was performed after birth, in 3 cases of renal failure in the first 2 weeks of life. The remaining cases were operated electively at an average age of 20 months. In 2 cases that underwent delayed surgical elective correction and in 1 of the 3 cases that underwent an emergency diversion, some degree of renal failure still persists. In our opinion, prenatal diagnosis, accurate postnatal urological workup and strict postoperative follow-up are fundamental to avoid the devastating consequences of CMSK on the affected child.

Original languageEnglish
Pages (from-to)205-209
Number of pages5
JournalFetal Diagnosis and Therapy
Issue number3
Publication statusPublished - May 1996


  • Congenital anomalies
  • Fetus
  • Kidney
  • Megaureter
  • Nuclear medicine
  • Ultrasound

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Pediatrics, Perinatology, and Child Health


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