Role of stapled and hand-sewn anastomoses in recurrence of Crohn's disease

Marco Scarpa, Imerio Angriman, Michela Barollo, Lnio Polese, Cesare Ruffolo, Matteo Bertin, Davide F. D'Amico

Research output: Contribution to journalArticle

Abstract

Background/Aims: Anastomotic recurrence after bowel resection is a major problem in Crohn's disease surgery. The aim of this study is to compare recurrence rate after stapled side-to-side ileo-colonic anastomosis to those after stapled end-to-side or hand-sewn side-to-side anastomosis to distinguish the role of suture technique and anastomotic configuration in the prevention of Crohn's disease recurrence. Methodology: Eighty-four consecutive patients who had undergone ileo-colonic resection for Crohn's disease were enrolled: 12 of them had stapled side-to-side anastomosis, 36 stapled end-to-side anastomosis and 36 hand-sewn side-to-side anastomosis. We evaluated duration of operation, first bowel movement after operation, postoperative hospital staying, post-operative surgical complications, clinical recurrence and reoperation rate. The statistical analysis was performed using Student's t-test and Fisher exact test. Cumulative recurrence rates were compared using F Cox test and Kaplan-Meier method. Results: No statistically significant difference between the three groups was observed in early post-operative follow up. The stapled side-to-side anastomosis group obtained a better symptom-free survival than the stapled end-to-side group (p=0.04). In the stapled and hand-sewn side-to-side groups reoperation rates were significantly lower than in the stapled end-to-side group (p=0.01 and p=0.05 respectively). Conclusions: All the three types of anastomosis were demonstrated to be equally safe in early post-operative outcome. A longer follow-up showed a significantly lower incidence of reoperation recurrence in the stapled and hand-sewn side-to-side anastomosis compared to the stapled end-to-side anastomosis group. This result may suggest the configuration of the anastomosis as the key point in the recurrence of anastomotic Crohn's disease.

Original languageEnglish
Pages (from-to)1053-1057
Number of pages5
JournalHepato-Gastroenterology
Volume51
Issue number58
Publication statusPublished - Jul 2004

Keywords

  • Crohn's disease
  • Hand-sewn anastomosis
  • Recurrence
  • Stapled anastomosis

ASJC Scopus subject areas

  • Gastroenterology

Fingerprint Dive into the research topics of 'Role of stapled and hand-sewn anastomoses in recurrence of Crohn's disease'. Together they form a unique fingerprint.

Cite this