Role of Stereotactic Body Radiation Therapy with Volumetric-Modulated Arcs and High-Intensity Photon Beams for the Treatment of Abdomino-Pelvic Lymph-Node Metastases

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Abstract

Aim: To study clinical outcome for oligometastatic patients (abdominal lymph-node metastases) treated with stereotactic body radiation therapy. Materials and methods: Seventy-one patients were studied retrospectively. Dose prescription was 45 Gy in six fractions. Clinical outcome was assessed with actuarial analysis. Results: The median follow-up was 1.5 years; 45 patients (63.3%) had solitary metastasis, and 26 (36.6%) had multiple lesions. Local control was achieved in 97.5% with a 1-year actuarial rate of 83%. Two-year progression-free survival was 63.1%, and the overall survival was 76.9%. Two patients (3%) developed grade 2 gastro-enteric toxicity. Conclusions: The treatment provided adequate clinical response in the management of oligometastatic cases.

Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalCancer Investigation
DOIs
Publication statusAccepted/In press - Jun 24 2016

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Keywords

  • Abdominal metastases
  • flattening filter-free beams
  • RapidArc
  • volumetric-modulated arc therapy

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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