Role of the Genetic Study in the Management of Carotid Body Tumor in Paraganglioma Syndrome

M. Antonello, M. Piazza, M. Menegolo, G. Opocher, G. P. Deriu, F. Grego

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Diagnosis of carotid body tumor (CBT) was made in a 36 years old woman. The pre-operative examination included genetic analysis of the succinate dehydrogenase that showed a mutation in his subunit D responsible of multiple paraganglioma at slow growth. Subsequently a thoraco-abdominal CT and indium111 octreotide body scan were performed and another paraganglioma was detected in the anterior mediastinum. CBT was surgically removed; differently the thoracic lesion due to his benign genetic profile was not treated. During a 3-years follow-up the thoracic paraganglioma as expected, didn't increase. Genetic analysis of succinate dehydrogenase, should be performed in the management of CBT.

Original languageEnglish
Pages (from-to)517-519
Number of pages3
JournalEuropean Journal of Vascular and Endovascular Surgery
Volume36
Issue number5
DOIs
Publication statusPublished - Nov 2008

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Carotid Body Tumor
Paraganglioma
Succinate Dehydrogenase
Thorax
Octreotide
Mediastinum
Mutation
Growth

Keywords

  • Carotid body tumor
  • Paraganglioma
  • Succinate dehydrogenase

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Role of the Genetic Study in the Management of Carotid Body Tumor in Paraganglioma Syndrome. / Antonello, M.; Piazza, M.; Menegolo, M.; Opocher, G.; Deriu, G. P.; Grego, F.

In: European Journal of Vascular and Endovascular Surgery, Vol. 36, No. 5, 11.2008, p. 517-519.

Research output: Contribution to journalArticle

Antonello, M. ; Piazza, M. ; Menegolo, M. ; Opocher, G. ; Deriu, G. P. ; Grego, F. / Role of the Genetic Study in the Management of Carotid Body Tumor in Paraganglioma Syndrome. In: European Journal of Vascular and Endovascular Surgery. 2008 ; Vol. 36, No. 5. pp. 517-519.
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