Abstract
Diagnosis of carotid body tumor (CBT) was made in a 36 years old woman. The pre-operative examination included genetic analysis of the succinate dehydrogenase that showed a mutation in his subunit D responsible of multiple paraganglioma at slow growth. Subsequently a thoraco-abdominal CT and indium111 octreotide body scan were performed and another paraganglioma was detected in the anterior mediastinum. CBT was surgically removed; differently the thoracic lesion due to his benign genetic profile was not treated. During a 3-years follow-up the thoracic paraganglioma as expected, didn't increase. Genetic analysis of succinate dehydrogenase, should be performed in the management of CBT.
| Original language | English |
|---|---|
| Pages (from-to) | 517-519 |
| Number of pages | 3 |
| Journal | European Journal of Vascular and Endovascular Surgery |
| Volume | 36 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Nov 2008 |
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Keywords
- Carotid body tumor
- Paraganglioma
- Succinate dehydrogenase
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Surgery
Cite this
Role of the Genetic Study in the Management of Carotid Body Tumor in Paraganglioma Syndrome. / Antonello, M.; Piazza, M.; Menegolo, M.; Opocher, G.; Deriu, G. P.; Grego, F.
In: European Journal of Vascular and Endovascular Surgery, Vol. 36, No. 5, 11.2008, p. 517-519.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Role of the Genetic Study in the Management of Carotid Body Tumor in Paraganglioma Syndrome
AU - Antonello, M.
AU - Piazza, M.
AU - Menegolo, M.
AU - Opocher, G.
AU - Deriu, G. P.
AU - Grego, F.
PY - 2008/11
Y1 - 2008/11
N2 - Diagnosis of carotid body tumor (CBT) was made in a 36 years old woman. The pre-operative examination included genetic analysis of the succinate dehydrogenase that showed a mutation in his subunit D responsible of multiple paraganglioma at slow growth. Subsequently a thoraco-abdominal CT and indium111 octreotide body scan were performed and another paraganglioma was detected in the anterior mediastinum. CBT was surgically removed; differently the thoracic lesion due to his benign genetic profile was not treated. During a 3-years follow-up the thoracic paraganglioma as expected, didn't increase. Genetic analysis of succinate dehydrogenase, should be performed in the management of CBT.
AB - Diagnosis of carotid body tumor (CBT) was made in a 36 years old woman. The pre-operative examination included genetic analysis of the succinate dehydrogenase that showed a mutation in his subunit D responsible of multiple paraganglioma at slow growth. Subsequently a thoraco-abdominal CT and indium111 octreotide body scan were performed and another paraganglioma was detected in the anterior mediastinum. CBT was surgically removed; differently the thoracic lesion due to his benign genetic profile was not treated. During a 3-years follow-up the thoracic paraganglioma as expected, didn't increase. Genetic analysis of succinate dehydrogenase, should be performed in the management of CBT.
KW - Carotid body tumor
KW - Paraganglioma
KW - Succinate dehydrogenase
UR - http://www.scopus.com/inward/record.url?scp=53449097249&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=53449097249&partnerID=8YFLogxK
U2 - 10.1016/j.ejvs.2008.06.021
DO - 10.1016/j.ejvs.2008.06.021
M3 - Article
C2 - 18692411
AN - SCOPUS:53449097249
VL - 36
SP - 517
EP - 519
JO - European Journal of Vascular and Endovascular Surgery
JF - European Journal of Vascular and Endovascular Surgery
SN - 1078-5884
IS - 5
ER -