Abstract
We analysed the phenotypic characteristics of mouse NK cells susceptible to boosting activity by T-cell-growth-factor (TCGF) and the characteristics of NK-cell progenitors able to grow in vitro in the presence of TCGF. Our data show that while both the above-mentioned cell populations are Asialo GM-1+, they differ in the expression of Thy 1 alloantigen. In addition, we also analysed the possible regulatory mechanisms capable of influencing the growth of TCGF-sensitive NK-cell progenitors. The data here reported suggest that the growth capability of NK cell progenitors is under the control of the thymus.
| Original language | English |
|---|---|
| Pages (from-to) | 401-408 |
| Number of pages | 8 |
| Journal | International Journal of Tissue Reactions |
| Volume | 6 |
| Issue number | 5 |
| Publication status | Published - 1984 |
ASJC Scopus subject areas
- Physiology
- Cell Biology