Ropivacaine infusion in diabetics subject with peripheral arterial diseasea prospective study

M. N D Di Minno, M. Milone, A. Russolillo, R. Lupoli, A. Di Minno, P. Maietta, C. Iacovazzo, G. Salvatore, F. Milone

Research output: Contribution to journalArticlepeer-review


Background: Peripheral arterial disease (PAD) predicts cardiovascular and cerebrovascular ischemic events. PAD treatment is aimed at reducing clinical symptoms, local tissue loss and at preventing complications. Aims:To evaluated the effect of peridural analgesia on peripheral perfusion and pain control. Methods: In 280 diabetic subjects with severe limb ischemia (65.7% males and 34.3% females, mean age 59.3±14.4 years) with a failure of medical treatment and contraindications to endovascular and/or surgical reperfusion, we performed a 30-day long peridural ropivacaine infusion, monitoring blood pressure, VAS and ABI periodically. Results: During ropivacaine infusion VAS significantly decreased (from 4.06±0.343 to 1.96±0.413, p

Original languageEnglish
Pages (from-to)91-93
Number of pages3
JournalExperimental and Clinical Endocrinology and Diabetes
Issue number2
Publication statusPublished - 2013


  • cardiovascular risk management
  • Diabetes
  • peripheral arterial disease

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine


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