Ropivacaine peritonsillar infiltration for analgesia after adenotonsillectomy in children: A randomized, double-blind, placebo-controlled Study

Marco Gemma, Lucia Oriella Piccioni, Luigi Gioia, Luigi Beretta, Mario Bussi

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13 Citations (Scopus)

Abstract

Objectives: Our randomized, double-blind, placebo-controlled study evaluates, the possible benefit of peritonsillar infiltration with 0.75% ropivacaine hydrochloride on the pain level after adanotonsillectomy in 3-to 7-year-old children. Methods: We randomly administered intraoperative peritonsillar infiltration with 0.2 mL/kg ropivacaine 0.75% (group R) or 0.2 mL/kg saline 0.9% (group F) to sixty 3-to 7-year-old children (ASA 1 or 2) who were undergoing adenotonsillectomy. Postoperative pain was assessed 6 and 24 hours after surgery by a 6-face Faces Pain Scale that allowed quantification of pain on a 100-mm horizontal line (0 = no pain). The number of rectal doses of acetaminophen-codeine required during the first postoperative day was recorded. Results: The pain scores did not differ between the groups, either 6 or 24 hours after surgery (group F, 43 ± 26, versus group R, 29 ± 23, and group F, 24 ± 23, versus group R, 30 ± 28, respectively). Acetaminophen-codeine doses were similarly required in the two groups. Conclusions: Peritonsillar infiltration with 0.75% ropivacaine does not provide any major postoperative analgesic effect in 3-to 7-year-old children after adenotonsillectomy. A possible clinically minor analgesia 6 hours after surgery is suggested.

Original languageEnglish
Pages (from-to)227-231
Number of pages5
JournalAnnals of Otology, Rhinology and Laryngology
Volume118
Issue number3
Publication statusPublished - Mar 2009

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Analgesia
Placebos
Pain
Facial Pain
Postoperative Pain
Analgesics
ropivacaine
codeine drug combination acetaminophen

Keywords

  • Adenotonsillectomy
  • Anesthesia postoperative pain
  • Ropivacaine

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

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title = "Ropivacaine peritonsillar infiltration for analgesia after adenotonsillectomy in children: A randomized, double-blind, placebo-controlled Study",
abstract = "Objectives: Our randomized, double-blind, placebo-controlled study evaluates, the possible benefit of peritonsillar infiltration with 0.75{\%} ropivacaine hydrochloride on the pain level after adanotonsillectomy in 3-to 7-year-old children. Methods: We randomly administered intraoperative peritonsillar infiltration with 0.2 mL/kg ropivacaine 0.75{\%} (group R) or 0.2 mL/kg saline 0.9{\%} (group F) to sixty 3-to 7-year-old children (ASA 1 or 2) who were undergoing adenotonsillectomy. Postoperative pain was assessed 6 and 24 hours after surgery by a 6-face Faces Pain Scale that allowed quantification of pain on a 100-mm horizontal line (0 = no pain). The number of rectal doses of acetaminophen-codeine required during the first postoperative day was recorded. Results: The pain scores did not differ between the groups, either 6 or 24 hours after surgery (group F, 43 ± 26, versus group R, 29 ± 23, and group F, 24 ± 23, versus group R, 30 ± 28, respectively). Acetaminophen-codeine doses were similarly required in the two groups. Conclusions: Peritonsillar infiltration with 0.75{\%} ropivacaine does not provide any major postoperative analgesic effect in 3-to 7-year-old children after adenotonsillectomy. A possible clinically minor analgesia 6 hours after surgery is suggested.",
keywords = "Adenotonsillectomy, Anesthesia postoperative pain, Ropivacaine",
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T1 - Ropivacaine peritonsillar infiltration for analgesia after adenotonsillectomy in children

T2 - A randomized, double-blind, placebo-controlled Study

AU - Gemma, Marco

AU - Piccioni, Lucia Oriella

AU - Gioia, Luigi

AU - Beretta, Luigi

AU - Bussi, Mario

PY - 2009/3

Y1 - 2009/3

N2 - Objectives: Our randomized, double-blind, placebo-controlled study evaluates, the possible benefit of peritonsillar infiltration with 0.75% ropivacaine hydrochloride on the pain level after adanotonsillectomy in 3-to 7-year-old children. Methods: We randomly administered intraoperative peritonsillar infiltration with 0.2 mL/kg ropivacaine 0.75% (group R) or 0.2 mL/kg saline 0.9% (group F) to sixty 3-to 7-year-old children (ASA 1 or 2) who were undergoing adenotonsillectomy. Postoperative pain was assessed 6 and 24 hours after surgery by a 6-face Faces Pain Scale that allowed quantification of pain on a 100-mm horizontal line (0 = no pain). The number of rectal doses of acetaminophen-codeine required during the first postoperative day was recorded. Results: The pain scores did not differ between the groups, either 6 or 24 hours after surgery (group F, 43 ± 26, versus group R, 29 ± 23, and group F, 24 ± 23, versus group R, 30 ± 28, respectively). Acetaminophen-codeine doses were similarly required in the two groups. Conclusions: Peritonsillar infiltration with 0.75% ropivacaine does not provide any major postoperative analgesic effect in 3-to 7-year-old children after adenotonsillectomy. A possible clinically minor analgesia 6 hours after surgery is suggested.

AB - Objectives: Our randomized, double-blind, placebo-controlled study evaluates, the possible benefit of peritonsillar infiltration with 0.75% ropivacaine hydrochloride on the pain level after adanotonsillectomy in 3-to 7-year-old children. Methods: We randomly administered intraoperative peritonsillar infiltration with 0.2 mL/kg ropivacaine 0.75% (group R) or 0.2 mL/kg saline 0.9% (group F) to sixty 3-to 7-year-old children (ASA 1 or 2) who were undergoing adenotonsillectomy. Postoperative pain was assessed 6 and 24 hours after surgery by a 6-face Faces Pain Scale that allowed quantification of pain on a 100-mm horizontal line (0 = no pain). The number of rectal doses of acetaminophen-codeine required during the first postoperative day was recorded. Results: The pain scores did not differ between the groups, either 6 or 24 hours after surgery (group F, 43 ± 26, versus group R, 29 ± 23, and group F, 24 ± 23, versus group R, 30 ± 28, respectively). Acetaminophen-codeine doses were similarly required in the two groups. Conclusions: Peritonsillar infiltration with 0.75% ropivacaine does not provide any major postoperative analgesic effect in 3-to 7-year-old children after adenotonsillectomy. A possible clinically minor analgesia 6 hours after surgery is suggested.

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