Rotational atherectomy followed by drug-eluting stent implantation in calcified coronary lesions

Shinichi Furuichi, Giuseppe M. Sangiorgi, Cosmo Godino, Flavio Airoldi, Matteo Montorfano, Alaide Chieffo, Iassen Michev, Mauro Carlino, Antonio Colombo

Research output: Contribution to journalArticle

Abstract

Aims: Little information is available on the outcome after rotational atherectomy (RA) followed by drug-eluting stent (DES) implantation in calcified coronary lesions. The aim of this study was to evaluate the outcome of patients with severe lesion calcification undergoing RA followed by implantation of DES. Methods and results: Ninety-five patients with 96 de novo severely calcified lesions were included. Twenty-nine patients (30.5%) had diabetes mellitus and seven patients (7.4%) had chronic renal failure. The total stent length per lesion was 48.4±24.9 mm. Procedural success rate was 95.8%. The incidence of cumulative major adverse cardiac events, defined as death, myocardial infarction (MI) and target vessel revascularisation (TVR), was 15.8% at the mean follow-up period of 14.7 months (range 6.0-57.7). Death occurred in four patients (4.2%). Non Q-wave MI occurred in 3 patients (3.2%) and Q-wave MI occurred in two patients (2.1%). The rate of target lesion revascularisation (TLR) was 9.5%. The rate of TVR was 11.6%. Two definite (2.1%) and 2 possible (2.1%) stent thromboses were observed. Conclusions: RA followed by DES implantation in severely calcified coronary lesions appears to be feasible including high rate of procedural success and low-incidence of TLR considering this complex lesion subset.

Original languageEnglish
Pages (from-to)370-374
Number of pages5
JournalEuroIntervention
Volume5
Issue number3
DOIs
Publication statusPublished - Aug 2009

Keywords

  • Calcified coronary lesions
  • Rotational atherectomy
  • Stents

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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