Abstract
The neural mechanisms and circuitry involved in levodopa-induced dyskinesia are unclear. Using repetitive transcranial magnetic stimulation (rTMS) over the supplementary motor area (SMA) in a group of patients with advanced Parkinson disease, the authors investigated whether modulation of SMA excitability may result in a modification of a dyskinetic state induced by continuous apomorphine infusion. rTMS at 1 Hz was observed to markedly reduce drug-induced dyskinesias, whereas 5-Hz rTMS induced a slight but not significant increase.
Original language | English |
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Pages (from-to) | 623-625 |
Number of pages | 3 |
Journal | Neurology |
Volume | 65 |
Issue number | 4 |
DOIs | |
Publication status | Published - Aug 23 2005 |
ASJC Scopus subject areas
- Neuroscience(all)