Rubella seroprofile of the Italian population: An 8-year comparison

Maria Cristina Rota, A. Bella, G. Gabutti, C. Giambi, A. Filia, M. Guido, A. De Donno, P. Crovari, M. L. Ciofi degli Atti

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The objective of this study is to evaluate how increasing MMR infant vaccination coverage in recent years has modified the epidemiology of rubella in Italy. A cross-sectional population-based seroprevalence study of rubella antibodies was conducted on 3094 sera, in 2004, and results were compared with data obtained by the same method in 1996. The overall proportion of rubella-seropositive individuals was found to be significantly higher in 2004 with respect to 1996 (84.6% vs. 77.4%). However, an increase in seropositivity was observed only in the 1-19 years age groups. Recent increases in childhood MMR vaccination coverage, therefore, have not had an impact on seroprevalence in women of childbearing age, over 5% of whom remain susceptible to rubella. Preconception screening and postpartum vaccination of susceptible women are fundamental if the WHO target of less than one case of congenital rubella syndrome per 100 000 live births is to be attained.

Original languageEnglish
Pages (from-to)555-562
Number of pages8
JournalEpidemiology and Infection
Volume135
Issue number4
DOIs
Publication statusPublished - May 2007

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Rubella
Vaccination
Seroepidemiologic Studies
Congenital Rubella Syndrome
Population
Live Birth
Postpartum Period
Italy
Epidemiology
Age Groups
Serum

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Immunology

Cite this

Rubella seroprofile of the Italian population : An 8-year comparison. / Rota, Maria Cristina; Bella, A.; Gabutti, G.; Giambi, C.; Filia, A.; Guido, M.; De Donno, A.; Crovari, P.; Ciofi degli Atti, M. L.

In: Epidemiology and Infection, Vol. 135, No. 4, 05.2007, p. 555-562.

Research output: Contribution to journalArticle

Rota, MC, Bella, A, Gabutti, G, Giambi, C, Filia, A, Guido, M, De Donno, A, Crovari, P & Ciofi degli Atti, ML 2007, 'Rubella seroprofile of the Italian population: An 8-year comparison', Epidemiology and Infection, vol. 135, no. 4, pp. 555-562. https://doi.org/10.1017/S0950268806007400
Rota MC, Bella A, Gabutti G, Giambi C, Filia A, Guido M et al. Rubella seroprofile of the Italian population: An 8-year comparison. Epidemiology and Infection. 2007 May;135(4):555-562. https://doi.org/10.1017/S0950268806007400
Rota, Maria Cristina ; Bella, A. ; Gabutti, G. ; Giambi, C. ; Filia, A. ; Guido, M. ; De Donno, A. ; Crovari, P. ; Ciofi degli Atti, M. L. / Rubella seroprofile of the Italian population : An 8-year comparison. In: Epidemiology and Infection. 2007 ; Vol. 135, No. 4. pp. 555-562.
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