Sézary Syndrome in a 17-Year-Old Boy: Clinicopathologic Features and Genomic Profile

Silvia Alberti-Violetti, Pamela Vezzoli, Laura Corti, Daniele Fanoni, Valentina Merlo, Luigia Venegoni, Alberto Reseghetti, Emilio Berti

Research output: Contribution to journalArticlepeer-review

Abstract

We describe the case of a 17-year-old Hispanic boy who had had erythroderma and diffuse lymphadenopathy for approximately 6 months. A diagnosis of Sézary syndrome was made on the basis of the histologic features of the skin; the presence of the same T-cell clone on the skin, blood, and bone marrow; and the high CD4+ lymphocyte count with an aberrant phenotype in peripheral blood; bone marrow involvement was also present. The patient was treated with systemic gemcitabine and achieved partial remission.

Original languageEnglish
Pages (from-to)e318-e321
JournalPediatric Dermatology
Volume33
Issue number5
DOIs
Publication statusPublished - Sep 1 2016

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Medicine(all)
  • Dermatology

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