Abstract
For a successfully treatment of the neurological form of Gaucher's Disease an early identification is necessary. Often an alteration of the horizontal saccadic eye movements constitutes the first sign of a central nervous system involvement In order to obtain an early identification of the neuronopathic forms of the disease, often masked by the use of the enzyme replacement therapy, the classical saccadic characteristics (Latency, Amplitude vs. Duration and Amplitude vs. Peak Velocity relationships) are not usable. This work studies if some other parameters (Mean Velocity/Peak Velocity, Kurtosis, Skewness, Asymmetry), able to describe the saccadic velocity profiles, could be considered to build an expert system able to reach the aim.
Original language | English |
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Title of host publication | Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings |
Pages | 699-702 |
Number of pages | 4 |
Volume | 26 I |
Publication status | Published - 2004 |
Event | Conference Proceedings - 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2004 - San Francisco, CA, United States Duration: Sep 1 2004 → Sep 5 2004 |
Other
Other | Conference Proceedings - 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2004 |
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Country/Territory | United States |
City | San Francisco, CA |
Period | 9/1/04 → 9/5/04 |
Keywords
- Eye movement
- Gaucher's disease
- Skwness
ASJC Scopus subject areas
- Bioengineering