Sacrococcigeal and vertebral chordomas. Report of three cases and review of the literature

M. Risio, C. Bagliani, R. Leli, P. Digirolamo, M. Del Pero, S. Coverliza

Research output: Contribution to journalArticle

Abstract

Three cases of sacrococcygeal and vertebral chordoma are described. Histogenetic and anatomopathological aspects with particular reference to differential diagnosis from similarly distributed neoplasias are discussed. Anti-cytoskeleton monoclonal antibodies were used to this purpose. The clinical profile of sacrococcygeal and vertebral chordomas is characterized by a pronounced metastatic potential; radiation treatment can only partially counter their biological behaviour, while chemotherapy has proved little or no effectiveness. Where possible, radical surgery is currently the only treatment to guarantee long-term survival or complete cure. Palliative surgery, associate with efficient painkilling, offers a better quality of life and slows down the progress of the disease.

Original languageEnglish
Pages (from-to)211-227
Number of pages17
JournalJournal of Neurosurgical Sciences
Volume29
Issue number3
Publication statusPublished - 1985

    Fingerprint

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Risio, M., Bagliani, C., Leli, R., Digirolamo, P., Del Pero, M., & Coverliza, S. (1985). Sacrococcigeal and vertebral chordomas. Report of three cases and review of the literature. Journal of Neurosurgical Sciences, 29(3), 211-227.