Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study

Jr Howard J.F.; K. Utsugisawa; M. Benatar; H. Murai; R.J. Barohn; I. Illa; S. Jacob; J. Vissing; T.M. Burns; J.T. Kissel; S. Muppidi; R.J. Nowak; F. O'Brien; J.-J. Wang; R. Mantegazza; C.G. Mazia; M. Wilken; C. Ortea; J. Saba; M. Rugiero; M. Bettini; G. Vidal; A.D. Garcia; P. Lamont; W.-K. Leong; H. Boterhoven; B. Fyfe; L. Roberts; M. Jasinarachchi; N. Willlems; J. Wanschitz; W. Löscher; J. De Bleecker; G. Van den Abeele; K. de Koning; K. De Mey; C. Miranda; S. Bonanno; C. Antozzi; L. Maggi; A. Campanella; C. Angelini; P. Cudia; V. Pegoraro; F. Bevilacqua; R. Iorio; M. Gabriele; S. Messina; A. Amato; S. Scala

doi:10.1016/S1474-4422(17)30369-1

Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study

Jr Howard J.F., K. Utsugisawa, M. Benatar, H. Murai, R.J. Barohn, I. Illa, S. Jacob, J. Vissing, T.M. Burns, J.T. Kissel, S. Muppidi, R.J. Nowak, F. O'Brien, J.-J. Wang, R. Mantegazza, C.G. Mazia, M. Wilken, C. Ortea, J. Saba, M. RugieroM. Bettini, G. Vidal, A.D. Garcia, P. Lamont, W.-K. Leong, H. Boterhoven, B. Fyfe, L. Roberts, M. Jasinarachchi, N. Willlems, J. Wanschitz, W. Löscher, J. De Bleecker, G. Van den Abeele, K. de Koning, K. De Mey, C. Miranda, S. Bonanno, C. Antozzi, L. Maggi, A. Campanella, C. Angelini, P. Cudia, V. Pegoraro, F. Bevilacqua, R. Iorio, M. Gabriele, S. Messina, A. Amato, S. Scala

Research output: Contribution to journal › Article › peer-review

Original language	Italian
Pages (from-to)	976-986
Number of pages	11
Journal	The Lancet Neurology
Volume	16
Issue number	12
DOIs	https://doi.org/10.1016/S1474-4422(17)30369-1
Publication status	Published - 2017

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10.1016/S1474-4422(17)30369-1

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85035019720&doi=10.1016%2fS1474-4422%2817%2930369-1&partnerID=40&md5=8949da7aedeeb0cef339c4e23f52ac28

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Howard J.F., J., Utsugisawa, K., Benatar, M., Murai, H., Barohn, R. J., Illa, I., Jacob, S., Vissing, J., Burns, T. M., Kissel, J. T., Muppidi, S., Nowak, R. J., O'Brien, F., Wang, J-J., Mantegazza, R., Mazia, C. G., Wilken, M., Ortea, C., Saba, J., ... Scala, S. (2017). Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study. The Lancet Neurology, 16(12), 976-986. https://doi.org/10.1016/S1474-4422(17)30369-1

Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study. / Howard J.F., Jr; Utsugisawa, K.; Benatar, M.; Murai, H.; Barohn, R.J.; Illa, I.; Jacob, S.; Vissing, J.; Burns, T.M.; Kissel, J.T.; Muppidi, S.; Nowak, R.J.; O'Brien, F.; Wang, J.-J.; Mantegazza, R.; Mazia, C.G.; Wilken, M.; Ortea, C.; Saba, J.; Rugiero, M.; Bettini, M.; Vidal, G.; Garcia, A.D.; Lamont, P.; Leong, W.-K.; Boterhoven, H.; Fyfe, B.; Roberts, L.; Jasinarachchi, M.; Willlems, N.; Wanschitz, J.; Löscher, W.; De Bleecker, J.; Van den Abeele, G.; de Koning, K.; De Mey, K.; Miranda, C.; Bonanno, S.; Antozzi, C.; Maggi, L.; Campanella, A.; Angelini, C.; Cudia, P.; Pegoraro, V.; Bevilacqua, F.; Iorio, R.; Gabriele, M.; Messina, S.; Amato, A.; Scala, S.

In: The Lancet Neurology, Vol. 16, No. 12, 2017, p. 976-986.

Research output: Contribution to journal › Article › peer-review

Howard J.F., J, Utsugisawa, K, Benatar, M, Murai, H, Barohn, RJ, Illa, I, Jacob, S, Vissing, J, Burns, TM, Kissel, JT, Muppidi, S, Nowak, RJ, O'Brien, F, Wang, J-J, Mantegazza, R, Mazia, CG, Wilken, M, Ortea, C, Saba, J, Rugiero, M, Bettini, M, Vidal, G, Garcia, AD, Lamont, P, Leong, W-K, Boterhoven, H, Fyfe, B, Roberts, L, Jasinarachchi, M, Willlems, N, Wanschitz, J, Löscher, W, De Bleecker, J, Van den Abeele, G, de Koning, K, De Mey, K, Miranda, C, Bonanno, S, Antozzi, C , Maggi, L, Campanella, A, Angelini, C , Cudia, P, Pegoraro, V, Bevilacqua, F, Iorio, R, Gabriele, M, Messina, S, Amato, A & Scala, S 2017, 'Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study', The Lancet Neurology, vol. 16, no. 12, pp. 976-986. https://doi.org/10.1016/S1474-4422(17)30369-1

Howard J.F. J, Utsugisawa K, Benatar M, Murai H, Barohn RJ, Illa I et al. Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study. The Lancet Neurology. 2017;16(12):976-986. https://doi.org/10.1016/S1474-4422(17)30369-1

Howard J.F., Jr ; Utsugisawa, K. ; Benatar, M. ; Murai, H. ; Barohn, R.J. ; Illa, I. ; Jacob, S. ; Vissing, J. ; Burns, T.M. ; Kissel, J.T. ; Muppidi, S. ; Nowak, R.J. ; O'Brien, F. ; Wang, J.-J. ; Mantegazza, R. ; Mazia, C.G. ; Wilken, M. ; Ortea, C. ; Saba, J. ; Rugiero, M. ; Bettini, M. ; Vidal, G. ; Garcia, A.D. ; Lamont, P. ; Leong, W.-K. ; Boterhoven, H. ; Fyfe, B. ; Roberts, L. ; Jasinarachchi, M. ; Willlems, N. ; Wanschitz, J. ; Löscher, W. ; De Bleecker, J. ; Van den Abeele, G. ; de Koning, K. ; De Mey, K. ; Miranda, C. ; Bonanno, S. ; Antozzi, C. ; Maggi, L. ; Campanella, A. ; Angelini, C. ; Cudia, P. ; Pegoraro, V. ; Bevilacqua, F. ; Iorio, R. ; Gabriele, M. ; Messina, S. ; Amato, A. ; Scala, S. / Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study. In: The Lancet Neurology. 2017 ; Vol. 16, No. 12. pp. 976-986.

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AU - Howard J.F., Jr

AU - Utsugisawa, K.

AU - Benatar, M.

AU - Murai, H.

AU - Barohn, R.J.

AU - Illa, I.

AU - Jacob, S.

AU - Vissing, J.

AU - Burns, T.M.

AU - Kissel, J.T.

AU - Muppidi, S.

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AU - O'Brien, F.

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AU - Mantegazza, R.

AU - Mazia, C.G.

AU - Wilken, M.

AU - Ortea, C.

AU - Saba, J.

AU - Rugiero, M.

AU - Bettini, M.

AU - Vidal, G.

AU - Garcia, A.D.

AU - Lamont, P.

AU - Leong, W.-K.

AU - Boterhoven, H.

AU - Fyfe, B.

AU - Roberts, L.

AU - Jasinarachchi, M.

AU - Willlems, N.

AU - Wanschitz, J.

AU - Löscher, W.

AU - De Bleecker, J.

AU - Van den Abeele, G.

AU - de Koning, K.

AU - De Mey, K.

AU - Miranda, C.

AU - Bonanno, S.

AU - Antozzi, C.

AU - Maggi, L.

AU - Campanella, A.

AU - Angelini, C.

AU - Cudia, P.

AU - Pegoraro, V.

AU - Bevilacqua, F.

AU - Iorio, R.

AU - Gabriele, M.

AU - Messina, S.

AU - Amato, A.

AU - Scala, S.

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