Abstract
Dumping syndrome (DS) is a complication of Nissen fundoplication. Dietary strategies can ameliorate symptoms, but this approach is not always foolproof. Limited evidence reports the efficacy of acarbose for children who are unresponsive to feeding manipulations. We report 8 patients with DS aged between 7 and 24 months. In 4 of 8 nutritional strategies failed, and acarbose treatment was started. The initial dose was 25 mg for meals, and increased until postprandial glucose was stable. In 3 of 4 children the final dose was higher than previously reported, without adverse effects. Acarbose is useful to treat DS in cases of failure of dietary strategies.
| Original language | English |
|---|---|
| Pages (from-to) | 113-114 |
| Number of pages | 2 |
| Journal | Journal of Pediatric Gastroenterology and Nutrition |
| Volume | 53 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jul 2011 |
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Keywords
- acarbose
- dumping syndrome
- hypoglycemia
ASJC Scopus subject areas
- Gastroenterology
- Pediatrics, Perinatology, and Child Health
Cite this
Safety and efficacy of high-dose acarbose treatment for dumping syndrome. / De Cunto, Angela; Barbi, Egidio; Minen, Federico; Ventura, Alessandro.
In: Journal of Pediatric Gastroenterology and Nutrition, Vol. 53, No. 1, 07.2011, p. 113-114.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Safety and efficacy of high-dose acarbose treatment for dumping syndrome
AU - De Cunto, Angela
AU - Barbi, Egidio
AU - Minen, Federico
AU - Ventura, Alessandro
PY - 2011/7
Y1 - 2011/7
N2 - Dumping syndrome (DS) is a complication of Nissen fundoplication. Dietary strategies can ameliorate symptoms, but this approach is not always foolproof. Limited evidence reports the efficacy of acarbose for children who are unresponsive to feeding manipulations. We report 8 patients with DS aged between 7 and 24 months. In 4 of 8 nutritional strategies failed, and acarbose treatment was started. The initial dose was 25 mg for meals, and increased until postprandial glucose was stable. In 3 of 4 children the final dose was higher than previously reported, without adverse effects. Acarbose is useful to treat DS in cases of failure of dietary strategies.
AB - Dumping syndrome (DS) is a complication of Nissen fundoplication. Dietary strategies can ameliorate symptoms, but this approach is not always foolproof. Limited evidence reports the efficacy of acarbose for children who are unresponsive to feeding manipulations. We report 8 patients with DS aged between 7 and 24 months. In 4 of 8 nutritional strategies failed, and acarbose treatment was started. The initial dose was 25 mg for meals, and increased until postprandial glucose was stable. In 3 of 4 children the final dose was higher than previously reported, without adverse effects. Acarbose is useful to treat DS in cases of failure of dietary strategies.
KW - acarbose
KW - dumping syndrome
KW - hypoglycemia
UR - http://www.scopus.com/inward/record.url?scp=79959837274&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79959837274&partnerID=8YFLogxK
U2 - 10.1097/MPG.0b013e31820ae6d1
DO - 10.1097/MPG.0b013e31820ae6d1
M3 - Article
C2 - 21694549
AN - SCOPUS:79959837274
VL - 53
SP - 113
EP - 114
JO - Journal of Pediatric Gastroenterology and Nutrition
JF - Journal of Pediatric Gastroenterology and Nutrition
SN - 0277-2116
IS - 1
ER -