Safety and efficacy of oral fluorescein angiography in detecting macular edema in comparison with spectral-domain optical coherence tomography

Giulio Barteselli, Jay Chhablani, Su Na Lee, Haiyan Wang, Sharif El Emam, Igor Kozak, Lingyun Cheng, Dirk Uwe Bartsch, Stanley Azen, William R. Freeman

Research output: Contribution to journalArticle

Abstract

PURPOSE:: To evaluate the safety of oral fluorescein angiography (FA) and to compare its efficacy in detection of macular edema (ME) with spectral-domain optical coherence tomography (SD-OCT). METHODS:: Results of imaging studies for 1,928 eyes of 1,019 patients who had simultaneously undergone both oral FA and SD-OCT by a confocal laser ophthalmoscope were reviewed. Sensitivity in detecting ME, discrepancy rate, and "kappa" agreement were determined for both the techniques and with eyes stratified by disease diagnosis. RESULTS:: No allergic reactions occurred after oral FA. Mild gastric discomfort was noted in

Original languageEnglish
Pages (from-to)1574-1583
Number of pages10
JournalRetina
Volume33
Issue number8
DOIs
Publication statusPublished - Sep 2013

Keywords

  • macular edema
  • oral fluorescein angiography
  • spectraldomain optical coherence tomography

ASJC Scopus subject areas

  • Ophthalmology

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  • Cite this

    Barteselli, G., Chhablani, J., Lee, S. N., Wang, H., El Emam, S., Kozak, I., Cheng, L., Bartsch, D. U., Azen, S., & Freeman, W. R. (2013). Safety and efficacy of oral fluorescein angiography in detecting macular edema in comparison with spectral-domain optical coherence tomography. Retina, 33(8), 1574-1583. https://doi.org/10.1097/IAE.0b013e318285cd84