Safety and efficacy of rt-PA treatment for acute stroke in pseudoxanthoma elasticum: the first report

Silvia Lanfranconi, Isabella Ghione, Gloria Valcamonica, Stefania Paola Corti, Sara Bonato, Nereo Bresolin

Research output: Contribution to journalArticle

Abstract

Pseudoxanthoma elasticum is a rare cause for ischaemic stroke. Little is known about acute and secondary prevention strategies in these subjects given the increased risk of gastrointestinal and urinary bleedings. Here we present the case of a 62 years old man affected by pseudoxanthoma elasticum who presented with acute ischaemic stroke and was successfully treated with intravenous thrombolysis. Neurological signs improved after intravenous thrombolysis without bleeding complication. To our knowledge, this is the first case of pseudoxanthoma elasticum—related stroke undergoing intravenous thrombolysis.

Original languageEnglish
JournalJournal of Thrombosis and Thrombolysis
DOIs
Publication statusAccepted/In press - Jan 1 2020

Keywords

  • Ischaemic stroke
  • Pseudoxanthoma elasticum
  • rt-PA
  • Thrombolysis

ASJC Scopus subject areas

  • Hematology
  • Cardiology and Cardiovascular Medicine

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