Abstract
Routine regional lymphadenectomy for colorectal liver metastases and primary liver tumors is still a subject for debate. During 2001-2005, we performed a prospective study of cases in which regional lymphadenectomy around the hepato-duodenal ligament and common hepatic artery was applied (group R? LN) or not (group R-LN). Pre-operative clinical features of patients were comparable among groups as well as the operative data. There were 108 (67%) males; the median age was 66 years; 124 cases had a single lesion (77%), and the median diameter was 4 cm. The type of lesion was: 77 (48%) colorectal liver metastases (M-CR), 75 (46%) hepatocellular carcinomas (HCC) and 10 (6%) cholangiocellular carcinomas. In the R? LN group, the mean number of lymph nodes removed was 6.7 ± 4.8 (range 4-26), and seven cases (8.6%) presented lymph node metastasis. The median follow-up was 3.5 years. M-CR patients showed comparable hospital mortality (R? LN 0% vs. R-LN 2.6%) and morbidity (R? LN 17.9% vs. R-LN 21.1%), but R? LN had higher 5-year disease-free survival (31 vs. 16%, p
Original language | English |
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Pages (from-to) | 27-34 |
Number of pages | 8 |
Journal | Updates in Surgery |
Volume | 62 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2010 |
Keywords
- HCC
- Hepatectomy
- Liver metastases
- Liver resection
- Lymphadenectomy
- Survival
ASJC Scopus subject areas
- Surgery