Safety of ciprofloxacin in neonates with sepsis

Maurizio Bonati, Chiara Pandolfini, Florentia Kaguelidou, Evelyne Jacqz-Aigrain, Mark Turner, Imti Choonara

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Newborn sepsis is a major cause of child mortality across the world. Strategies for prevention and treatment have the potential to save many newborns from a sepsis-related death. Among the various parenteral antibiotic options possible, there is considerable experience with the use of penicillins, cephalosporins, and aminoglycosides. Ciprofloxacin is also increasingly accepted as safe in the neonate. However, the available evidence is not of high quality, and adequate research is required to specifically address dosage schedules, safety, and efficacy of ciprofloxacin to lead to established interventions to reduce morbidity and mortality for neonatal sepsis.

Original languageEnglish
Pages (from-to)1019-1022
Number of pages4
JournalAdverse Drug Reaction Bulletin
Issue number265
DOIs
Publication statusPublished - Dec 2010

Fingerprint

Ciprofloxacin
Sepsis
Safety
Child Mortality
Aminoglycosides
Cephalosporins
Penicillins
Appointments and Schedules
Anti-Bacterial Agents
Morbidity
Mortality
Research
Neonatal Sepsis

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

Cite this

Safety of ciprofloxacin in neonates with sepsis. / Bonati, Maurizio; Pandolfini, Chiara; Kaguelidou, Florentia; Jacqz-Aigrain, Evelyne; Turner, Mark; Choonara, Imti.

In: Adverse Drug Reaction Bulletin, No. 265, 12.2010, p. 1019-1022.

Research output: Contribution to journalArticle

Bonati, Maurizio ; Pandolfini, Chiara ; Kaguelidou, Florentia ; Jacqz-Aigrain, Evelyne ; Turner, Mark ; Choonara, Imti. / Safety of ciprofloxacin in neonates with sepsis. In: Adverse Drug Reaction Bulletin. 2010 ; No. 265. pp. 1019-1022.
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