Sagittal abdominal diameter is more predictive of cardiovascular risk than abdominal fat compartments in severe obesity

G. Guzzaloni, A. Minocci, P. Marzullo, A. Liuzzi

Research output: Contribution to journalArticle


Objective: To compare the predictive role of abdominal fat distribution by computed tomography (CT) with that of total abdominal fat by sagittal abdominal diameter (SAD) on cardiovascular risk in severe obesity. Design: A cross-sectional, clinical study. Subjects: 64 males and 64 females, aged 42±15 years (mean±s.d.; range 18-75 years), BMI (kg/m2) 41.7±5.3 (30.2-57.6). Measurements: Blood glucose, total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, triglycerides (TGLs), insulin (IRI), insulin resistance (HOMA-IR), slice areas (cm2) of total (tSAT), superficial (sSAT) and deep subcutaneous adipose tissue (dSAT), visceral adipose tissue (VAT) and SAD (mm) by CT. Results: The sSAT depot was negatively associated with blood glucose, HOMA-IR, LDL cholesterol and TGLs, whereas dSAT was negatively associated with HDL cholesterol. VAT was associated with blood glucose and HOMA-IR, whereas SAD was associated with all variables evaluated. In males, VAT was associated with blood glucose (r2=0.12, P2=0.67, P2=0.65, P2=0.67, P2=0.63, P2=0.21, P<0.001), total cholesterol (r2=0.16, P2=0.20, P2=0.12, P2=0.52, P2=0.53, P2=0.52, P2=0.54, P2=0.52, P2=0.51, P

Original languageEnglish
Pages (from-to)233-238
Number of pages6
JournalInternational Journal of Obesity
Issue number2
Publication statusPublished - Feb 20 2009



  • Abdominal fat
  • Cardiovascular risk factors
  • Computed tomography
  • Sagittal abdominal diameter

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics
  • Endocrinology, Diabetes and Metabolism

Cite this