Salivary calculi microbiota: new insights into microbial networks and pathogens reservoir

Roberta De Grandi, Pasquale Capaccio, Alessandro Bidossi, Marta Bottagisio, Lorenzo Drago, Sara Torretta, Lorenzo Pignataro, Elena De Vecchi

Research output: Contribution to journalArticlepeer-review


Sialolithiasis represents the most common disorders of salivary glands in middle-aged patients. It has been hypothesized that the retrograde migration of bacteria from the oral cavity to gland ducts may facilitate the formation of stones. Thus, in the present study, a microbiome characterization of salivary calculi was performed to evaluate the abundance and the potential correlations between microorganisms constituting the salivary calculi microbiota. Our data supported the presence of a core microbiota of sialoliths constituted principally by Streptococcus spp., Fusobacterium spp. and Eikenella spp., along with the presence of important pathogens commonly involved in infective sialoadenitis.

Original languageEnglish
Pages (from-to)109-112
JournalMicrobes and Infection
Issue number2
Publication statusPublished - 2019


  • Biofilm
  • Microbial network
  • Microbiota
  • Salivary calculi
  • Sialoadenitis
  • Sialolithiasis

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Infectious Diseases


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