Salivary levels of thallium in acute human poisoning

P. Richelmi, F. Bono, L. Guardia, B. Ferrini, L. Manzo

Research output: Contribution to journalArticle

Abstract

Thallium intoxication in a 28-year-old woman was characterized by neurological and gastrointestinal symptoms and alopecia. Treatment was started 4 days after poisoning and consisted of forced diuresis and administration of Prussian Blue at four daily doses of 5 g by duodenal tube for 20 days. Thallium was measured by atomic absorption spectrophotometry in urine, faeces and saliva. Considerable amounts of thallium were detected in saliva, salivary concentrations being up to 15 times higher than urinary ones. Evidence was also obtained that only a little fraction of the ingested dose was excreted by the intestine during the hospital course in spite of Prussian Blue administration.

Original languageEnglish
Pages (from-to)321-325
Number of pages5
JournalArchives of Toxicology
Volume43
Issue number4
DOIs
Publication statusPublished - Feb 1980

Fingerprint

Thallium
Poisoning
Saliva
Atomic Spectrophotometry
Diuresis
Alopecia
Spectrophotometry
Feces
Intestines
Urine
ferric ferrocyanide
Therapeutics

Keywords

  • Alopecia
  • Neuropathy
  • Prussian Blue
  • Salivary excretion
  • Thallium poisoning

ASJC Scopus subject areas

  • Toxicology
  • Health, Toxicology and Mutagenesis

Cite this

Richelmi, P., Bono, F., Guardia, L., Ferrini, B., & Manzo, L. (1980). Salivary levels of thallium in acute human poisoning. Archives of Toxicology, 43(4), 321-325. https://doi.org/10.1007/BF00366188

Salivary levels of thallium in acute human poisoning. / Richelmi, P.; Bono, F.; Guardia, L.; Ferrini, B.; Manzo, L.

In: Archives of Toxicology, Vol. 43, No. 4, 02.1980, p. 321-325.

Research output: Contribution to journalArticle

Richelmi, P, Bono, F, Guardia, L, Ferrini, B & Manzo, L 1980, 'Salivary levels of thallium in acute human poisoning', Archives of Toxicology, vol. 43, no. 4, pp. 321-325. https://doi.org/10.1007/BF00366188
Richelmi P, Bono F, Guardia L, Ferrini B, Manzo L. Salivary levels of thallium in acute human poisoning. Archives of Toxicology. 1980 Feb;43(4):321-325. https://doi.org/10.1007/BF00366188
Richelmi, P. ; Bono, F. ; Guardia, L. ; Ferrini, B. ; Manzo, L. / Salivary levels of thallium in acute human poisoning. In: Archives of Toxicology. 1980 ; Vol. 43, No. 4. pp. 321-325.
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