Abstract
CCNU and methotrexate were employed as salvage treatment in 34 small cell lung cancer patients resistant to CAV/PE alternating induction chemotherapy. In the 33 evaluable patients we observed an objective response rate of 21.2% and 3% complete response; median survival was 4 months with 2 patients alive 18 months from starting salvage chemotherapy. The treatment was well tolerated. CCNU and methotrexate has shown to be a moderately active and tolerable salvage treatment for small cell lung cancer after CAV/PE alternating first-line chemotherapy.
Original language | English |
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Pages (from-to) | 506-510 |
Number of pages | 5 |
Journal | Tumori |
Volume | 77 |
Issue number | 6 |
Publication status | Published - 1991 |
ASJC Scopus subject areas
- Cancer Research