Salvia somalensis essential oil as a potential cosmetic ingredient: Solvent-free microwave extraction, hydrodistillation, GC-MS analysis, odour evaluation and in vitro cytotoxicity assays

C. Villa, B. Trucchi, A. Bertoli, L. Pistelli, A. Parodi, A. M. Bassi, B. Ruffoni

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Salvia somalensis Vatke, a wild sage native of Somalia, has been studied with the aim of assessing the potential cosmetic application of its essential oil, recovered from fresh aerial parts by solvent-free microwave extraction - SFME. To evaluate the efficiency and reliability of this ecofriendly procedure, the recovery of the essential oil was also processed by conventional hydrodistillation (HD) and the results compared. The essential oils obtained by both SFME and HD were analysed by gas chromatography-mass spectrometry using apolar and polar capillary columns. The essential oil recovered by SFME was submitted to an odour evaluation that revealed peculiar olfactive characteristics interesting in alcoholic male perfumery and body detergents.In vitro cytotoxicity assays were carried out using NCTC 2544 human keratinocytes as target cells. The oil displayed slight cytotoxic effects, which were three orders of magnitude lower than those found for sodium dodecyl sulphate positive control. The promising results in terms of chemical composition, scent and safety seem to indicate this essential oil as an interesting potential functional ingredient useful in a cosmetic context.

Original languageEnglish
Pages (from-to)55-61
Number of pages7
JournalInternational Journal of Cosmetic Science
Volume31
Issue number1
DOIs
Publication statusPublished - Feb 2009

Fingerprint

Salvia
Essential oils
Cosmetics
Odors
Volatile Oils
Cytotoxicity
Microwaves
Assays
Somalia
Detergents
Sodium dodecyl sulfate
Keratinocytes
Sodium Dodecyl Sulfate
Gas chromatography
Gas Chromatography-Mass Spectrometry
Mass spectrometry
Oils
In Vitro Techniques
Odorants
Antennas

Keywords

  • GC-MS analysis
  • In vitro cytotoxicity
  • Odour evaluation
  • Salvia somalensis essential oil
  • Solvent-free microwave extraction

ASJC Scopus subject areas

  • Dermatology
  • Colloid and Surface Chemistry
  • Ageing
  • Drug Discovery
  • Pharmaceutical Science
  • Chemistry (miscellaneous)

Cite this

Salvia somalensis essential oil as a potential cosmetic ingredient : Solvent-free microwave extraction, hydrodistillation, GC-MS analysis, odour evaluation and in vitro cytotoxicity assays. / Villa, C.; Trucchi, B.; Bertoli, A.; Pistelli, L.; Parodi, A.; Bassi, A. M.; Ruffoni, B.

In: International Journal of Cosmetic Science, Vol. 31, No. 1, 02.2009, p. 55-61.

Research output: Contribution to journalArticle

@article{9143f6722f974a80b3219bdde90fcd28,
title = "Salvia somalensis essential oil as a potential cosmetic ingredient: Solvent-free microwave extraction, hydrodistillation, GC-MS analysis, odour evaluation and in vitro cytotoxicity assays",
abstract = "Salvia somalensis Vatke, a wild sage native of Somalia, has been studied with the aim of assessing the potential cosmetic application of its essential oil, recovered from fresh aerial parts by solvent-free microwave extraction - SFME. To evaluate the efficiency and reliability of this ecofriendly procedure, the recovery of the essential oil was also processed by conventional hydrodistillation (HD) and the results compared. The essential oils obtained by both SFME and HD were analysed by gas chromatography-mass spectrometry using apolar and polar capillary columns. The essential oil recovered by SFME was submitted to an odour evaluation that revealed peculiar olfactive characteristics interesting in alcoholic male perfumery and body detergents.In vitro cytotoxicity assays were carried out using NCTC 2544 human keratinocytes as target cells. The oil displayed slight cytotoxic effects, which were three orders of magnitude lower than those found for sodium dodecyl sulphate positive control. The promising results in terms of chemical composition, scent and safety seem to indicate this essential oil as an interesting potential functional ingredient useful in a cosmetic context.",
keywords = "GC-MS analysis, In vitro cytotoxicity, Odour evaluation, Salvia somalensis essential oil, Solvent-free microwave extraction",
author = "C. Villa and B. Trucchi and A. Bertoli and L. Pistelli and A. Parodi and Bassi, {A. M.} and B. Ruffoni",
year = "2009",
month = "2",
doi = "10.1111/j.1468-2494.2008.00480.x",
language = "English",
volume = "31",
pages = "55--61",
journal = "International Journal of Cosmetic Science",
issn = "0142-5463",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Salvia somalensis essential oil as a potential cosmetic ingredient

T2 - Solvent-free microwave extraction, hydrodistillation, GC-MS analysis, odour evaluation and in vitro cytotoxicity assays

AU - Villa, C.

AU - Trucchi, B.

AU - Bertoli, A.

AU - Pistelli, L.

AU - Parodi, A.

AU - Bassi, A. M.

AU - Ruffoni, B.

PY - 2009/2

Y1 - 2009/2

N2 - Salvia somalensis Vatke, a wild sage native of Somalia, has been studied with the aim of assessing the potential cosmetic application of its essential oil, recovered from fresh aerial parts by solvent-free microwave extraction - SFME. To evaluate the efficiency and reliability of this ecofriendly procedure, the recovery of the essential oil was also processed by conventional hydrodistillation (HD) and the results compared. The essential oils obtained by both SFME and HD were analysed by gas chromatography-mass spectrometry using apolar and polar capillary columns. The essential oil recovered by SFME was submitted to an odour evaluation that revealed peculiar olfactive characteristics interesting in alcoholic male perfumery and body detergents.In vitro cytotoxicity assays were carried out using NCTC 2544 human keratinocytes as target cells. The oil displayed slight cytotoxic effects, which were three orders of magnitude lower than those found for sodium dodecyl sulphate positive control. The promising results in terms of chemical composition, scent and safety seem to indicate this essential oil as an interesting potential functional ingredient useful in a cosmetic context.

AB - Salvia somalensis Vatke, a wild sage native of Somalia, has been studied with the aim of assessing the potential cosmetic application of its essential oil, recovered from fresh aerial parts by solvent-free microwave extraction - SFME. To evaluate the efficiency and reliability of this ecofriendly procedure, the recovery of the essential oil was also processed by conventional hydrodistillation (HD) and the results compared. The essential oils obtained by both SFME and HD were analysed by gas chromatography-mass spectrometry using apolar and polar capillary columns. The essential oil recovered by SFME was submitted to an odour evaluation that revealed peculiar olfactive characteristics interesting in alcoholic male perfumery and body detergents.In vitro cytotoxicity assays were carried out using NCTC 2544 human keratinocytes as target cells. The oil displayed slight cytotoxic effects, which were three orders of magnitude lower than those found for sodium dodecyl sulphate positive control. The promising results in terms of chemical composition, scent and safety seem to indicate this essential oil as an interesting potential functional ingredient useful in a cosmetic context.

KW - GC-MS analysis

KW - In vitro cytotoxicity

KW - Odour evaluation

KW - Salvia somalensis essential oil

KW - Solvent-free microwave extraction

UR - http://www.scopus.com/inward/record.url?scp=58149316068&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=58149316068&partnerID=8YFLogxK

U2 - 10.1111/j.1468-2494.2008.00480.x

DO - 10.1111/j.1468-2494.2008.00480.x

M3 - Article

C2 - 19134128

AN - SCOPUS:58149316068

VL - 31

SP - 55

EP - 61

JO - International Journal of Cosmetic Science

JF - International Journal of Cosmetic Science

SN - 0142-5463

IS - 1

ER -