Sarcoidosis and major histocompatibility complex genes with special emphasis of BF F subtypes

O. Finco, M. Martinetti, E. Dondi, M. Luisetti, L. Pasturenzi, M. Cuccia

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Frequencies for HLA class I and II histoglobulins and C4A, C4B, BF complement proteins were performed for 59 sarcoidosis patients. The DR5 allele was present in 55.9% of patients as compared to 31.5% of controls. We noticed that its increase was more relevant in males and in those with a poor prognosis. BF F allele was significantly overrepresented in patients (29.09% vs. 19.15% of control), especially in women. Special emphasis was given to BF F subtyping, to define an association between a particular BF F subtype and patient's sex or disease outcome.

Original languageEnglish
Pages (from-to)80-85
Number of pages6
JournalComplement and Inflammation
Volume8
Issue number2
Publication statusPublished - 1991

Fingerprint

Sarcoidosis
Major Histocompatibility Complex
Genes
Alleles
Complement System Proteins

Keywords

  • BF F subtypes
  • heterogeneity
  • major histocompatibility complex genes
  • sarcoidosis

ASJC Scopus subject areas

  • Immunology
  • Hematology

Cite this

Sarcoidosis and major histocompatibility complex genes with special emphasis of BF F subtypes. / Finco, O.; Martinetti, M.; Dondi, E.; Luisetti, M.; Pasturenzi, L.; Cuccia, M.

In: Complement and Inflammation, Vol. 8, No. 2, 1991, p. 80-85.

Research output: Contribution to journalArticle

Finco, O, Martinetti, M, Dondi, E, Luisetti, M, Pasturenzi, L & Cuccia, M 1991, 'Sarcoidosis and major histocompatibility complex genes with special emphasis of BF F subtypes', Complement and Inflammation, vol. 8, no. 2, pp. 80-85.
Finco, O. ; Martinetti, M. ; Dondi, E. ; Luisetti, M. ; Pasturenzi, L. ; Cuccia, M. / Sarcoidosis and major histocompatibility complex genes with special emphasis of BF F subtypes. In: Complement and Inflammation. 1991 ; Vol. 8, No. 2. pp. 80-85.
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