Sarcopenia (and sarcopenic obesity) in older patients with gynecological malignancies

Research output: Contribution to journalArticlepeer-review


Cancer is often complicated by the deterioration of both muscle mass and function, which may be more pronounced in older people. The prevalence of sarcopenia varies according to tumour type, stage and sarcopenia definition; in gynaecologic malignancies it ranges from 25 to 50%. Unfortunately, sarcopenia is often underdiagnosed especially in overweight and obese patients. The consequences of sarcopenia are serious: shorter time of tumour progression, increased chemotherapy-related toxicity, post-operative complications, poor functional status, hospitalisation, increased length of hospital stay, high 30-day readmission rate and mortality. Therefore, its precocious recognition and treatment is of paramount importance. We demonstrated that obesity can mask sarcopenia, taking into consideration a sample of older patient with cancer, unless body composition evaluation and comprehensive geriatric assessment, including measures of muscle strength and performance, is executed. Our work underlines the importance of a multidisciplinary approach to older patients with cancer to optimize their management.

Original languageEnglish
Pages (from-to)467-469
Number of pages3
JournalJournal of Geriatric Oncology
Issue number3
Publication statusPublished - Apr 2021


  • Aged
  • Body Composition
  • Female
  • Genital Neoplasms, Female/complications
  • Humans
  • Muscle Strength
  • Muscle, Skeletal/pathology
  • Obesity/complications
  • Prevalence
  • Sarcopenia/diagnosis


Dive into the research topics of 'Sarcopenia (and sarcopenic obesity) in older patients with gynecological malignancies'. Together they form a unique fingerprint.

Cite this