SARS-CoV, influenza A and syncitial respiratory virus resistance against common disinfectants and ultraviolet irradiation

Filippo Ansaldi, F. Banfi, P. Morelli, L. Valle, P. Durando, L. Sticchi, S. Contos, R. Gasparini, P. Crovari

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

To evaluate the virucidal efficacy of six commonly used chemical disinfectants, and ultraviolet radiation (U.V.) against SARS-CoV and compare it to the resistance of other airborne viruses, such as Influenza and Respiratory Sincytial Virus, a salt solution containing a standard concentration of cell-grown viruses, was mixed with a larger volume of different disinfectants at their use dilution and the mixtures were held for a defined contact time. The virucidal efficacy of disinfectants and U.V. was evaluated by infectivity, detected by inoculation of samples in suitable cell culture and genome integrity, detected by nested RT-PCR. SARS-CoV as well as RSV seem to be sensible to the different disinfectants tested in our study and U.V. radiation, while influenza virus appear to be more resistant in particular to the action of chlorhexidine digluconate and benzalkonium-chloride. In consideration of the possible infectious role of SARS-CoV RNA, sodium hypochlorite 0.1% appear to be the more efficacious disinfectant for surfaces and hands potentially contaminated with respiratory viruses and SARS-CoV.

Original languageEnglish
Pages (from-to)5-8
Number of pages4
JournalJournal of Preventive Medicine and Hygiene
Volume45
Issue number1-2
Publication statusPublished - Mar 2004

Fingerprint

SARS Virus
Disinfectants
Human Influenza
Radiation
Viruses
Hand Sanitizers
Benzalkonium Compounds
Sodium Hypochlorite
Orthomyxoviridae
Cell Culture Techniques
Salts
Genome
RNA
Polymerase Chain Reaction

Keywords

  • Disinfectants
  • SARS-CoV
  • Virucidal efficacy

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Ansaldi, F., Banfi, F., Morelli, P., Valle, L., Durando, P., Sticchi, L., ... Crovari, P. (2004). SARS-CoV, influenza A and syncitial respiratory virus resistance against common disinfectants and ultraviolet irradiation. Journal of Preventive Medicine and Hygiene, 45(1-2), 5-8.

SARS-CoV, influenza A and syncitial respiratory virus resistance against common disinfectants and ultraviolet irradiation. / Ansaldi, Filippo; Banfi, F.; Morelli, P.; Valle, L.; Durando, P.; Sticchi, L.; Contos, S.; Gasparini, R.; Crovari, P.

In: Journal of Preventive Medicine and Hygiene, Vol. 45, No. 1-2, 03.2004, p. 5-8.

Research output: Contribution to journalArticle

Ansaldi, F, Banfi, F, Morelli, P, Valle, L, Durando, P, Sticchi, L, Contos, S, Gasparini, R & Crovari, P 2004, 'SARS-CoV, influenza A and syncitial respiratory virus resistance against common disinfectants and ultraviolet irradiation', Journal of Preventive Medicine and Hygiene, vol. 45, no. 1-2, pp. 5-8.
Ansaldi, Filippo ; Banfi, F. ; Morelli, P. ; Valle, L. ; Durando, P. ; Sticchi, L. ; Contos, S. ; Gasparini, R. ; Crovari, P. / SARS-CoV, influenza A and syncitial respiratory virus resistance against common disinfectants and ultraviolet irradiation. In: Journal of Preventive Medicine and Hygiene. 2004 ; Vol. 45, No. 1-2. pp. 5-8.
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