Schizencephaly: Prenatal diagnosis by computed sonography and magnetic resonance imaging

M. Lituania, U. Passamonti, M. S. Cordone, G. M. Magnano, P. Toma

Research output: Contribution to journalArticlepeer-review


Magnetic resonance (MR) imaging was performed at 29 weeks of pregnancy after ultrasonographic detection of an abnormal cleft in the fetal brain. Fetal neuromuscular blockade was induced by pancuronium bromide injected into the umbilical vein under continuous ultrasound (US) guidance. MR images supported the echotomographic diagnosis of schizencephaly improving the visualization of symmetrical broad clefts connecting the lateral ventricles with the subarachnoid space. Schizencephaly was finally confirmed by neonatal US, computed tomography, and MR.

Original languageEnglish
Pages (from-to)649-655
Number of pages7
JournalPrenatal Diagnosis
Issue number9
Publication statusPublished - 1989

ASJC Scopus subject areas

  • Genetics(clinical)
  • Obstetrics and Gynaecology


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