Schizofrenia e funzioni cognitive: Una revisione critica della letteratura 2. Significato, implicazioni e trattamento dei deficit cognitivi

Translated title of the contribution: Schizophrenia and cognitive functioning: 2. Meaning, implications and treatment of cognitive deficits

James Gold, Giovanni De Girolamo, Luisa Brambilla, Stefano Cappa, Fausto Mazzi, Kathy O'Donnell, Valnea Scala, Rosaria Pioli

Research output: Contribution to journalArticle

Abstract

In the first part of this paper we have reviewed the large body of research showing that multiple deficits in various cognitive functions represent a fairly consistent finding in patients with schizophrenia. The second part of this review focuses on the existing relationship between cognitive impairment and psychosocial functioning: cognitive deficits seem to play a major role on patients' patterns of social and vocational functioning; the implications of these findings for rehabilitation are also discussed, and the more recent attempts to design specific programmes of cognitive rehabilitation are presented. Moreover, the effects of pharmacotherapy with conventional and atypical antipsychotic drugs on cognitive functions are critically analyzed: although some studies have demonstrated that new atypical antipsychotics may have a greater beneficial effect on cognitive functioning as compared to traditional neuroleptics, it remains to be ascertained if these effects are widespread, long lasting and associated with a concomitant improvement in psychosocial functioning. Some data seem to show that the main effect of new atypical antipsychotics may be represented by the absence of impairments in practice effects, which is translated in a better performance on various neuropsychological tests. Overall the effects of new antipsychotic drugs on cognitive functioning and the benefits and limits of cognitive rehabilitation represent important areas to be addressed by future research.

Translated title of the contributionSchizophrenia and cognitive functioning: 2. Meaning, implications and treatment of cognitive deficits
Original languageItalian
Pages (from-to)53-60
Number of pages8
JournalRivista di Psichiatria
Volume37
Issue number2
Publication statusPublished - 2002

ASJC Scopus subject areas

  • Psychiatry and Mental health

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