Schizophrenic patients before and after HIV infection: A case-control study

M. C. Mauri, L. Fabiano, S. Bravin, C. Ricci, G. Invernizzi

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Thirteen HIV positive schizophrenic patients (Group 1), age ranging from 23 to 60 years, diagnosed as schizophrenics (DSM IV), were studied during a four week hospitalization period, due to an acute exacerbation phase. The patients were treated with haloperidol (3-15 mg/die p.o.) and diazepam (2-25 mg/die p.o.). Clinical picture and side-effects were assessed by BPRS, HRS- A, HRS-D, and DOTES, at admission and after 2, 3, 4 weeks of hospitalization period (Time 5, 7, 8, 9). Clinical evaluations were compared to a previous hospitalization period, before seroconversion (Time 0, 2, 3, 4), and to a control group (Group 2) of HIV negative schizophrenic patients (11 pb) followed as well during 2 periods of hospitalization. Our data seem to emphasize that the HIV infection could induce organic alterations in the CNS which might cause psychopathological consequences: significantly more severe depressive symptomatology and a reduction of tolerability to neuroleptics in the seroconverted patients' group.

Original languageEnglish
Pages (from-to)437-441
Number of pages5
JournalEncephale
Volume23
Issue number6
Publication statusPublished - Nov 1997

Fingerprint

HIV Infections
Case-Control Studies
Hospitalization
HIV-2
Haloperidol
Diazepam
Diagnostic and Statistical Manual of Mental Disorders
Antipsychotic Agents
Age Groups
HIV
Control Groups
Infection
AIDS/HIV

Keywords

  • Depression
  • HIV infection
  • Neuroleptic tolerability
  • Schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Neuroscience(all)

Cite this

Mauri, M. C., Fabiano, L., Bravin, S., Ricci, C., & Invernizzi, G. (1997). Schizophrenic patients before and after HIV infection: A case-control study. Encephale, 23(6), 437-441.

Schizophrenic patients before and after HIV infection : A case-control study. / Mauri, M. C.; Fabiano, L.; Bravin, S.; Ricci, C.; Invernizzi, G.

In: Encephale, Vol. 23, No. 6, 11.1997, p. 437-441.

Research output: Contribution to journalArticle

Mauri, MC, Fabiano, L, Bravin, S, Ricci, C & Invernizzi, G 1997, 'Schizophrenic patients before and after HIV infection: A case-control study', Encephale, vol. 23, no. 6, pp. 437-441.
Mauri MC, Fabiano L, Bravin S, Ricci C, Invernizzi G. Schizophrenic patients before and after HIV infection: A case-control study. Encephale. 1997 Nov;23(6):437-441.
Mauri, M. C. ; Fabiano, L. ; Bravin, S. ; Ricci, C. ; Invernizzi, G. / Schizophrenic patients before and after HIV infection : A case-control study. In: Encephale. 1997 ; Vol. 23, No. 6. pp. 437-441.
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