Schwann cells-axon interaction in myelination

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

The remarkable interaction between glial cells and axons is crucial for nervous system development and homeostasis. Alterations in this continuous communication can cause severe pathologies that can compromise the integrity of the nervous system. The most dramatic consequence of this interaction is the generation of the myelin sheath, made by myelinating glial cells: Schwann cells in the peripheral nervous system and oligodendrocytes in the central nervous system. In this review I will focus on signals coming from axons in the first part and then on those from Schwann cells that promote the formation and the maintenance of peripheral myelin. I will discuss their inter-relationship together with seminal and important advances recently made.

Original languageEnglish
Pages (from-to)24-29
Number of pages6
JournalCurrent Opinion in Neurobiology
Volume39
DOIs
Publication statusPublished - Aug 1 2016

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Schwann Cells
Myelin Sheath
Cell Communication
Neuroglia
Nervous System
Axons
Oligodendroglia
Peripheral Nervous System
Homeostasis
Central Nervous System
Maintenance
Pathology

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Schwann cells-axon interaction in myelination. / Taveggia, Carla.

In: Current Opinion in Neurobiology, Vol. 39, 01.08.2016, p. 24-29.

Research output: Contribution to journalArticle

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