Scintigraphic oesophageal clearance in diabetics: Clinical usefulness

Vincenzo Frusciante, Sergio Modoni, Adriano Bonazza, Salvatore De Cosmo, Filippo Barbano, Luciano Lucentini, Pier Giuseppe Paleani Vettori

Research output: Contribution to journalArticlepeer-review


The whole digestive tract is one of the sites most involved in diabetic autonomic neuropathy. The aim of this work was to validate the clinical usefulness of oesophageal scintigraphy in the early detection of this complication, of diabetes. Eighty-one diabetic patients without oesophageal symptoms were studied by solid meal scintigraphic test (SMST) and 35 out of them also by liquid meal scintigraphic test (LMST). As controls, 20 normal volunteers were studied by LMST and 14 by SMST. Forty-seven diabetics studied by SMST were also evaluated by cardiovascular tests (CT) and for the presence of retinopathy and peripheral neuropathy. The most statistically significant difference between diabetics and controls was found at 75s with SMST. SMST results showed a statistically significant correlation with CT. No correlation was found with the presence of retinopathy or peripheral neuropathy. We conclude that SMST is a useful, safe, low-cost diagnostic tool in the detection of diabetic autonomic neuropathy.

Original languageEnglish
Pages (from-to)955-964
Number of pages10
JournalNuclear Medicine Communications
Issue number12
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


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