We report a case of temporal lobe epilepsy (TLE) with hippocampal sclerosis and familial febrile convulsions (6 subjects including the patient) in whom two sodium channel alpha-subunit (SCN1A) gene mutations were detected (one never reported). Our data confirm that SCN1A mutations can be responsible for febrile seizures (FS) and TLE further than generalized epilepsy with FS plus (GEFS+) and severe myoclonic epilepsy of infancy (SMEI).
|Translated title of the contribution||SCN1A mutations in a case of temporal lobe epilepsy with hippocampal sclerosis and familial febrile convulsions|
|Number of pages||2|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - 2008|
ASJC Scopus subject areas
- Clinical Neurology