TY - JOUR
T1 - Screening for Aphasia in NeuroDegeneration for the Diagnosis of Patients with Primary Progressive Aphasia
T2 - Clinical Validity and Psychometric Properties
AU - Battista, Petronilla
AU - Catricalà, Eleonora
AU - Piccininni, Marco
AU - Copetti, Massimiliano
AU - Esposito, Valentina
AU - Polito, Cristina
AU - Miozzo, Antonio
AU - Gobbi, Elena
AU - Cuoco, Sofia
AU - Boschi, Veronica
AU - Picillo, Marina
AU - Sorbi, Sandro
AU - Barone, Paolo
AU - Iannaccone, Sandro
AU - Garrard, Peter
AU - Logroscino, Giancarlo
AU - Cappa, Stefano F.
PY - 2018/10
Y1 - 2018/10
N2 - Background: We evaluated the psychometric proprieties of the Screening for Aphasia in NeuroDegeneration (SAND) battery in Italian primary progressive aphasia (PPA) and movement disorder (MD) patients. Methods: The sample included 30 consecutive PPA and 45 MD patients who completed the SAND battery together with a clinical interview and a neurological/neuropsychological examination and 130 healthy controls (HC). Results: The SAND battery showed good internal consistency and good convergent and divergent validity. receiver operating characteristic analysis revealed an area under the curve of 0.978 for PPA versus HC and of 0.786 for PPA versus MD. A cutoff ≥3 gave a sensitivity of 0.933% and a specificity of 0.946% for discriminating PPA versus HC, whereas a cutoff ≥5 gave a sensitivity of 0.767% and a specificity of 0.667% for discriminating PPA versus MD. Conclusion: These results indicate that the SAND battery is an adequate, reliable, and valid diagnostic tool for PPA.
AB - Background: We evaluated the psychometric proprieties of the Screening for Aphasia in NeuroDegeneration (SAND) battery in Italian primary progressive aphasia (PPA) and movement disorder (MD) patients. Methods: The sample included 30 consecutive PPA and 45 MD patients who completed the SAND battery together with a clinical interview and a neurological/neuropsychological examination and 130 healthy controls (HC). Results: The SAND battery showed good internal consistency and good convergent and divergent validity. receiver operating characteristic analysis revealed an area under the curve of 0.978 for PPA versus HC and of 0.786 for PPA versus MD. A cutoff ≥3 gave a sensitivity of 0.933% and a specificity of 0.946% for discriminating PPA versus HC, whereas a cutoff ≥5 gave a sensitivity of 0.767% and a specificity of 0.667% for discriminating PPA versus MD. Conclusion: These results indicate that the SAND battery is an adequate, reliable, and valid diagnostic tool for PPA.
KW - Dementia
KW - Diagnostic accuracy
KW - Language impairment
KW - Screening instrument
KW - Speech-language assessment
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U2 - 10.1159/000492632
DO - 10.1159/000492632
M3 - Article
AN - SCOPUS:85055767781
SP - 243
EP - 252
JO - Dementia and Geriatric Cognitive Disorders
JF - Dementia and Geriatric Cognitive Disorders
SN - 1420-8008
ER -