Screening of maternal serum for prenatal Down's syndrome and neural tube defects: An Italian experience

M. Cioffi, P. Gazzerro, C. Di MacChia, M. T. Vietri, A. Contursi, R. Magnetta, R. Colicigno, V. Sica

Research output: Contribution to journalArticle

Abstract

Serum AFP, uE3, β-HCGare all non-invasive techniques able to identify pregnant women at high risk of Down's syndrome and neural tube defects (NTD). We collected 1017 sera from pregnant women (age range: 18-41 years; gestation: 15-21 weeks). It is important that to calculate Down's syndrome risk to be sure what population parameters in computer software are used, and how appropriate these are for the population being screened. Our results from the risky pregnancies show an acceptable agreement between the Triple tests and amniocentesis.

Original languageEnglish
Pages (from-to)177-181
Number of pages5
JournalImmuno-Analyse et Biologie Specialisee
Volume15
Issue number3
DOIs
Publication statusPublished - May 2000

Keywords

  • triple test / Down's syndrome / NTD / prenatal diagnosis
  • triple test / trisomie 21 / défaut de fermeture du tube neural / diagnostic prénatal

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

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