Screening spirometry to detect respiratory allergy

I. Cirillo, C. Klersy, G. Marseglia, M. Tosca, G. Ciprandi

Research output: Contribution to journalArticlepeer-review


Background: Recently, it has been evidenced that the forced expiratory flow at the 25 and 75% of the pulmonary volume (FEF25-75) might be considered as a possible marker of early bronchial impairment in patients with allergic rhinitis alone. Objectives: The aim of this study was to determine whether a spirometric impairment may predict allergy during screening visit. Methods: The study included 283 Navy soldiers (255 males, mean age 27.1 + 8.2) who had to undergo spirometry for attending specific courses. Fifty-four showed slight spirometric anomalies. Thus, they referred to Navy Hospital of La Spezia for standardized tests: skin prick test, spirometry, and methacholine bronchial challenge. Results: Forty seven (87%) subjects were sensitized (47% monosensitized and 53% polysensitized). Allergic rhinitis was diagnosed in 25 subjects with median nasal TSS 5. FVC and FEV1 values were normal, whereas FEF25-75 values were reduced (61.8 + 14.8% of predicted), bronchodilation test was significant for FEF25-75 (82.9 + 16.8% of predicted; p

Original languageEnglish
Pages (from-to)146-148
Number of pages3
JournalEuropean Annals of Allergy and Clinical Immunology
Issue number5
Publication statusPublished - May 2006


  • Bronchial hyperreactivity
  • FEF
  • Rhinitis
  • Sensitization
  • Spirometry

ASJC Scopus subject areas

  • Immunology and Allergy


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