TY - JOUR
T1 - Searching for evidence to support the use of ginger in the prevention of chemotherapy-induced nausea and vomiting
AU - Bossi, Paolo
AU - Cortinovis, Diego
AU - Cossu Rocca, Maria
AU - Roila, Fausto
AU - Seminara, Patrizia
AU - Fabi, Alessandra
AU - Canova, Stefania
AU - Verri, Elena
AU - Fatigoni, Sonia
AU - Iannace, Alessandro
AU - Macchi, Fabio
AU - Ripamonti, Carla
PY - 2016/6/1
Y1 - 2016/6/1
N2 - Patients with cancer frequently use dietary supplementation and herbal therapies to control symptoms of disease and adverse effects of cancer therapy. Despite the widespread use of dietary supplementation and herbal therapies in oncology, robust scientific evidence in this area is lacking. Not only do these products need to be tested in large and well-designed observational or randomized studies, but their manufacturing process must be improved to achieve higher levels of standardization in product quality. Ginger is frequently used to counteract chemotherapy-induced nausea and vomiting (CINV), and some suggestions that it might be effective against CINV come from randomized and/or crossover clinical trials. However, several limitations in the methods of these studies limit their power and generalizability. The authors are conducting a randomized, double-blind study with a large sample size and homogeneous inclusion criteria in order to evaluate the efficacy of a well-standardized ginger extract in reducing nausea in patients with cancer. The widespread use of standardized herbal therapies and natural components among patients requires that scientific and rigorous research strategies are applied in this field to guide the physicians and the patients in safer use.
AB - Patients with cancer frequently use dietary supplementation and herbal therapies to control symptoms of disease and adverse effects of cancer therapy. Despite the widespread use of dietary supplementation and herbal therapies in oncology, robust scientific evidence in this area is lacking. Not only do these products need to be tested in large and well-designed observational or randomized studies, but their manufacturing process must be improved to achieve higher levels of standardization in product quality. Ginger is frequently used to counteract chemotherapy-induced nausea and vomiting (CINV), and some suggestions that it might be effective against CINV come from randomized and/or crossover clinical trials. However, several limitations in the methods of these studies limit their power and generalizability. The authors are conducting a randomized, double-blind study with a large sample size and homogeneous inclusion criteria in order to evaluate the efficacy of a well-standardized ginger extract in reducing nausea in patients with cancer. The widespread use of standardized herbal therapies and natural components among patients requires that scientific and rigorous research strategies are applied in this field to guide the physicians and the patients in safer use.
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U2 - 10.1089/acm.2015.0315
DO - 10.1089/acm.2015.0315
M3 - Article
AN - SCOPUS:84975321866
VL - 22
SP - 486
EP - 488
JO - Journal of Alternative and Complementary Medicine
JF - Journal of Alternative and Complementary Medicine
SN - 1075-5535
IS - 6
ER -