Second case of hepatoblastoma in a young patient with Simpson-Golabi-Behmel syndrome

Paola Sabrina Buonuomo, A. Ruggiero, I. Vasta, G. Attinà, R. Riccardi, G. Zampino

Research output: Contribution to journalArticle

Abstract

Simpson-Golabi-Behmel syndrome (SGBS) is an X-linked overgrowth syndrome associated with multiple congenital anomalies caused by a mutant X-linked recessive trait. The authors report on a 14-month-old male patient affected by hepatoblastoma. As far as is known, this is the second patient reported with SGBS and hepatoblastoma. The observations emphasize that an increased risk of neoplasia in SGBS must be kept in mind, especially in young patients.

Original languageEnglish
Pages (from-to)623-628
Number of pages6
JournalPediatric Hematology and Oncology
Volume22
Issue number7
DOIs
Publication statusPublished - Oct 2005

Keywords

  • GPC3 gene
  • Hepatoblastoma
  • Overgrowth syndrome
  • Simpson-Golabi-Behmel syndrome

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology
  • Cancer Research

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