Secondary aneurysmal bone cyst in Langerhans cell histiocytosis: Case report, literature review

P. Lomoro, I. Simonetti, G. Vinci, V. Fichera, L. Tarotto, P. Trovato, M. S. Prevedoni Gorone

Research output: Contribution to journalArticle

Abstract

Langerhans cell histiocytosis (LCH) is a rare disease of the myeloid precursor cells, it predominantly occurs in the skull and long bones as unifocal bone lesions. Aneurysmal bone cysts (ABC) are benign, expansive and lytic bone. Reports of secondary ABC occurring in LCH are rare, having only been reported twice in the skull. Here, we report the first case of LCH masquerading as ABC in a 14-month-old female child who presented with a rapidly growing mass in her left femur. The lesion had typical radiological features of ABC, and only histological examination revealed the presence of cells suggestive of LCH.

Original languageEnglish
Pages (from-to)97-100
Number of pages4
JournalEuropean Journal of Radiology Open
Volume6
DOIs
Publication statusPublished - Jan 1 2019

Keywords

  • Aneurysmal bone cysts (ABC)
  • Langerhans cell histiocytosis (LCH)
  • Magnetic resonance imaging (MRI)
  • Pediatric bone tumors
  • Radiograph (X-ray)

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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