TY - JOUR
T1 - Secondary prevention of early-onset sepsis
T2 - A less invasive Italian approach for managing neonates at risk
AU - Berardi, Alberto
AU - Tzialla, Chryssoula
AU - Travan, Laura
AU - Bua, Jenny
AU - Santori, Daniele
AU - Azzalli, Milena
AU - Spada, Caterina
AU - Lucaccioni, Laura
PY - 2018/6/28
Y1 - 2018/6/28
N2 - Strategies to prevent early-onset sepsis (EOS) have led to a substantial decline in many countries. However, one of the most controversial topics in neonatology is the management of asymptomatic full-term and late preterm neonates at risk for EOS, and guidelines lack substantial consensus regarding this issue. A strategy for managing neonates, entirely based on serial physical examinations, has been developed in two Italian regions. This strategy seems safe, while reducing laboratory tests and unnecessary antibiotics. In the current commentary we provide area-based data concerning the prevention of EOS in 2 northern Italian regions, and we detail the results of their strategy for managing healthy-appearing newborns at risk for EOS.
AB - Strategies to prevent early-onset sepsis (EOS) have led to a substantial decline in many countries. However, one of the most controversial topics in neonatology is the management of asymptomatic full-term and late preterm neonates at risk for EOS, and guidelines lack substantial consensus regarding this issue. A strategy for managing neonates, entirely based on serial physical examinations, has been developed in two Italian regions. This strategy seems safe, while reducing laboratory tests and unnecessary antibiotics. In the current commentary we provide area-based data concerning the prevention of EOS in 2 northern Italian regions, and we detail the results of their strategy for managing healthy-appearing newborns at risk for EOS.
KW - Group B streptococcus
KW - Intrapartum antibiotic prophylaxis
KW - Neonatal sepsis
KW - Newborn infant
KW - Prevention
KW - Risk factors
UR - http://www.scopus.com/inward/record.url?scp=85049172521&partnerID=8YFLogxK
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U2 - 10.1186/s13052-018-0515-8
DO - 10.1186/s13052-018-0515-8
M3 - Review article
AN - SCOPUS:85049172521
VL - 44
JO - Italian Journal of Pediatrics
JF - Italian Journal of Pediatrics
SN - 1720-8424
IS - 1
M1 - 73
ER -