Prevenzione secondaria dell'ictus mediante riduzione della pressione arteriosa.

Translated title of the contribution: Secondary prevention of stroke through arterial blood pressure reduction

G. Mancia, G. Grassi

Research output: Contribution to journalArticlepeer-review


Large scale observational studies have conclusively demonstrated that systolic and diastolic blood pressure values are linearly related to the incidence of cerebrovascular diseases and that high blood pressure is an important risk factor for both primary and secondary development of stroke. Interventional studies have shown that blood pressure lowering by antihypertensive treatment reduces the incidence of stroke in hypertensive patients without a history of previous stroke. Whether this is the case also for the secondary prevention of cerebral ischemic attacks has not been unequivocally shown, however. The PROGRESS ("Perindopril Protection Against Recurrent Stroke Study") study has been designed and is under way to collect information on this important issue of the antihypertensive treatment, its purpose being to evaluate the blood pressure lowering effects with an ACE-inhibitor on recurrent stroke in an overall population of 6000 patients with a positive history of previous cerebral ischemic attacks or stroke.

Translated title of the contributionSecondary prevention of stroke through arterial blood pressure reduction
Original languageItalian
Pages (from-to)715-719
Number of pages5
Issue number7
Publication statusPublished - Jul 1997

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Secondary prevention of stroke through arterial blood pressure reduction'. Together they form a unique fingerprint.

Cite this