Secretion of growth hormone releasing hormone in obese children

S. Loche, S. Balzano, M. Bozzola, A. Moretta, S. Pintus, A. Faedda, A. Muntoni, D. Carta, C. Pintor

Research output: Contribution to journalArticlepeer-review

Abstract

We have evaluated baseline and I-dopa-stimulated peripheral growth hormone releasing hormone (pGHRH) secretion in 6 obese prepubertal children and in 7 age-matched controls. Baseline pGHRH levels were no different between obese (36.6±9.8 pg/ml, mean±SE) and control children (40.6±10.1 pg/ml). Administration of I-dopa (500 mg po) caused a significant increase of pGHRH levels in both the obese (65.3±19.8 pg/ml, p

Original languageEnglish
Pages (from-to)453-457
Number of pages5
JournalJournal of Endocrinological Investigation
Volume15
Issue number6
DOIs
Publication statusPublished - 1992

Keywords

  • GH
  • GHRH
  • obesity
  • somatostatin

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

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