Segregation of virulent influenza A(H1N1) variants in the lower respiratory tract of critically ill patients during the 2010-2011 seasonal epidemic

Antonio Piralla, Elena Pariani, Francesca Rovida, Giulia Campanini, Alba Muzzi, Vincenzo Emmi, Giorgio A. Iotti, Antonio Pesenti, Pier Giulio Conaldi, Alessandro Zanetti, Fausto Baldanti

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Since its appearance in 2009, the pandemic influenza A(H1N1) virus circulated worldwide causing several severe infections. Methods: Respiratory samples from patients with 2009 influenza A(H1N1) and acute respiratory distress attending 24 intensive care units (ICUs) as well as from patients with lower respiratory tract infections not requiring ICU admission and community upper respiratory tract infections in the Lombardy region (10 million inhabitants) of Italy during the 2010-2011 winter-spring season, were analyzed. Results: In patients with severe ILI, the viral load was higher in bronchoalveolar lavage (BAL) with respect to nasal swab (NS), (p

Original languageEnglish
Article numbere28332
JournalPLoS One
Volume6
Issue number12
DOIs
Publication statusPublished - Dec 14 2011

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Fingerprint Dive into the research topics of 'Segregation of virulent influenza A(H1N1) variants in the lower respiratory tract of critically ill patients during the 2010-2011 seasonal epidemic'. Together they form a unique fingerprint.

Cite this