Abstract
Herein, we report a 26-year-old patient with lymphangiomatosis of the spleen associated with multiple lymphatic and venous malformations. This patient underwent excision of a large lymphatic malformation of the left abdominal wall during childhood. A venous malformation of her left lower limb was excised during adolescence. Additional lymphatic malformations were found in the soft tissue of her left thigh at the age of 20. During hospitalization for a huge vulvar hemangioma at the age of 26, she was incidentally found to have asymptomatic splenomegaly, for which she underwent splenectomy. Examination of the spleen revealed diffuse involvement by a lymphatic anomaly predominantly forming small cystic spaces. Lymphangiomatosis of the spleen is rare and is classically separated into an isolated or pure form and a generalized form when it is associated with involvement of other viscera and/or multiple soft-tissue planes. This patient was affected by a borderline form of splenic lymphangiomatosis with limited somatic involvement of the superficial soft tissues and blood vessels. Notably, all the additional vascular malformations in this patient were left sided, and at this time there was no additional involvement of internal organ. No hereditary or known syndrome was identified.
| Original language | English |
|---|---|
| Pages (from-to) | 291-299 |
| Number of pages | 9 |
| Journal | Advances in Anatomic Pathology |
| Volume | 21 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2014 |
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Keywords
- lymphangiomatosis
- lymphatic malformation
- multiple cysts of spleen
- splenomegaly
- venous malformation
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Anatomy
- Medicine(all)
Cite this
Selected case from the Arkadi M. Rywlin international pathology slide series : Lymphangiomatosis of the spleen associated with ipsilateral abdominopelvic and lower extremity venolymphatic malformations: A case report and review of the literature. / Bisceglia, Michele; Chiaramonte, Antonio; Lauriola, Walter; Galliani, Carlos A.; Musto, Pellegrino; Colacchio, Giovanni.
In: Advances in Anatomic Pathology, Vol. 21, No. 4, 2014, p. 291-299.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Selected case from the Arkadi M. Rywlin international pathology slide series
T2 - Lymphangiomatosis of the spleen associated with ipsilateral abdominopelvic and lower extremity venolymphatic malformations: A case report and review of the literature
AU - Bisceglia, Michele
AU - Chiaramonte, Antonio
AU - Lauriola, Walter
AU - Galliani, Carlos A.
AU - Musto, Pellegrino
AU - Colacchio, Giovanni
PY - 2014
Y1 - 2014
N2 - Herein, we report a 26-year-old patient with lymphangiomatosis of the spleen associated with multiple lymphatic and venous malformations. This patient underwent excision of a large lymphatic malformation of the left abdominal wall during childhood. A venous malformation of her left lower limb was excised during adolescence. Additional lymphatic malformations were found in the soft tissue of her left thigh at the age of 20. During hospitalization for a huge vulvar hemangioma at the age of 26, she was incidentally found to have asymptomatic splenomegaly, for which she underwent splenectomy. Examination of the spleen revealed diffuse involvement by a lymphatic anomaly predominantly forming small cystic spaces. Lymphangiomatosis of the spleen is rare and is classically separated into an isolated or pure form and a generalized form when it is associated with involvement of other viscera and/or multiple soft-tissue planes. This patient was affected by a borderline form of splenic lymphangiomatosis with limited somatic involvement of the superficial soft tissues and blood vessels. Notably, all the additional vascular malformations in this patient were left sided, and at this time there was no additional involvement of internal organ. No hereditary or known syndrome was identified.
AB - Herein, we report a 26-year-old patient with lymphangiomatosis of the spleen associated with multiple lymphatic and venous malformations. This patient underwent excision of a large lymphatic malformation of the left abdominal wall during childhood. A venous malformation of her left lower limb was excised during adolescence. Additional lymphatic malformations were found in the soft tissue of her left thigh at the age of 20. During hospitalization for a huge vulvar hemangioma at the age of 26, she was incidentally found to have asymptomatic splenomegaly, for which she underwent splenectomy. Examination of the spleen revealed diffuse involvement by a lymphatic anomaly predominantly forming small cystic spaces. Lymphangiomatosis of the spleen is rare and is classically separated into an isolated or pure form and a generalized form when it is associated with involvement of other viscera and/or multiple soft-tissue planes. This patient was affected by a borderline form of splenic lymphangiomatosis with limited somatic involvement of the superficial soft tissues and blood vessels. Notably, all the additional vascular malformations in this patient were left sided, and at this time there was no additional involvement of internal organ. No hereditary or known syndrome was identified.
KW - lymphangiomatosis
KW - lymphatic malformation
KW - multiple cysts of spleen
KW - splenomegaly
KW - venous malformation
UR - http://www.scopus.com/inward/record.url?scp=84902290193&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84902290193&partnerID=8YFLogxK
U2 - 10.1097/PAP.0000000000000031
DO - 10.1097/PAP.0000000000000031
M3 - Article
C2 - 24911254
AN - SCOPUS:84902290193
VL - 21
SP - 291
EP - 299
JO - Advances in Anatomic Pathology
JF - Advances in Anatomic Pathology
SN - 1072-4109
IS - 4
ER -