Abstract
The B203.13 monoclonal antibody specifically recognizes a subset (8- 18.5%) of human CD34+ haemopoietic progenitors, which are significantly (P+/B203.13+ showed a greater number of cells/colony with respect to CD34+/B203.13-; (ii) after 10d of liquid cultures with 100ng/ml of thrombopoietin, only a minority of CD34-derived cells positive for CD41 coexpressed B203.13; (iii) in situ immunocytochemical staining revealed that B203.13 was expressed exclusively on immature megakaryoblasts; (iv) circulating platelets did not express B203.13.
| Original language | English |
|---|---|
| Pages (from-to) | 766-769 |
| Number of pages | 4 |
| Journal | British Journal of Haematology |
| Volume | 99 |
| Issue number | 4 |
| Publication status | Published - 1997 |
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Keywords
- Cell differentiation
- Megakaryocytes
- Platelets
ASJC Scopus subject areas
- Hematology
Cite this
Vitale, M., Zauli, G., Bassini, A., Visani, G., Rezzani, R., Croce, C. M., & Manzoli, F. A. (1997). Selective enrichment in human megakaryocyte progenitors by the B203.13 surface differentiation antigen. British Journal of Haematology, 99(4), 766-769.